Search Results for: us stem cell

Weekly reads: heterochromatin, H3.3, Mesoblast bump

N-myc, heterochromatin

My lab is focused in part on chromatin states in stem cells and cancer including heterochromatin. In fact, my lab’s website is chromatin.com. Heterochromatin is dense, often inactive chromatin. By H&E staining and electron microscopy, heterochromatin looks dark compared to the rest of the nucleus, largely composed of euchromatin. Toward the end of my postdoc […]

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Weekly reads: AL embryos ruling, blasting cancer, marrow organoids, beef inside rice plants

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Are small clusters of cells that make up 5-day-old human embryos equivalent to children? Biologically and in terms of just common sense, the answer is “no.” These tiny spheres have around 100 cells and no organs. Actual people have many trillions of cells, brains, and other organs. Alabama law on embryos may block IVF About

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Man could get 240 yrs for amniotic fluid for knees Medicare scam

A Justice Department press release details how a physician’s assistant (PA) in Texas was convinced of fraud related to amniotic fluid injections. This story tells us some important things about how Medicare handles things versus the FDA approach to such things. Amniotic fluid scam A jury found Ray Anthony Shoulders, a PA at a pain

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Weekly reads: Xist & autoimmune disease in women, Crohn’s disease, dumb headline of the week

Xist ,auto immune disease

Readers of The Niche have asked me many questions about stem cells for autoimmune disease but the puzzle of why women get these conditions more often than men hasn’t come up before here. For instance, why is MS so much more common in women than men? It’s remained somewhat of a mystery over the years.

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Fountain Life update: lawsuit by doc, high performance aging, Celularity trial plan

Fountain Life

A New Rochelle doctor has filed suit against the healthcare clinic firm Fountain Life alleging fraud. Now seems like a good time for an update on the firm. Peter Diamandis along with Bob Hariri, life coach Tony Robbins, and surgeon William Kapp founded Fountain Life, an early detection-focused healthcare company. Are they also a longevity firm? To

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Weekly reads: Vertex & CRISPR Therapeutics, Arnold Caplan death, MS genetics

CRISPR Therapeutics

The biotechs Vertex and CRISPR Therapeutics have an interesting relationship as biotechs. They are partners are multiple levels but also are very different as companies including in size. There’s been a key development in one of their partnerships. Before we jump into that, please check out the video version of my 20 stem cell and

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Dishing on biobots like xenobots & anthrobots vs. organoids

Anthrobots

If you remember xenobots, mobile clusters of frog cells, now you might be interested to learn that some of the same team brings us human cell clusters called anthrobots. Both frog and human cellular clusters are considered types of biobots or robots made of cells. To me, anthrobots seem akin to human organoids or assembloids.

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Weekly reads: game of clones, super-SOX, Moonwalk Bio, Great Wall’s living skin

dog clones

I’m trying to remember the first time I ever heard about clones. It had to be as a kid. Maybe in a monster movie or TV show? Possibly a clone was referred to by the more general term “double”, which is not necessarily a clone. Whatever it was, I’m sure as a kid that I

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2023 The Screamers Science Hype Award goes to anti-aging media coverage

The Screamers Science Hype Awards.

Every year I give out The Screamers Science Hype Award. The point of The Screamers is to raise awareness about science hype and catalyze new ways to combat it. In that spirit, I award what I see as the most extreme examples of science hype. Sometimes in addition to the one main winner, I give “honorable”

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Can trying to cheat death paradoxically kill you sooner?

anti-aging, Dorian Gray

Can you paradoxically kill yourself early by trying to cheat Death? For example, die through risky anti-aging approaches? The question came to mind because such longevity efforts have become more extreme. They also get more hype in the media. I’ve been following the anti-aging space mainly because many interventions involve risky stem cell injections. Those

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