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Weekly reads: freeze-dried cloning, FDA signals, stem cell escapees

July 10, 2022 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Cloning is one of those topics that both fascinates and kind of scares people, especially the idea of duplicating people. I regularly cover the topic here on The Niche because stem cell technologies are involved. Also, one form of the process sometimes called “therapeutic cloning” involves embryonic stem cells. Duplicating mammals has now long been […]

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Giostar stem cell clinic chain review, red flags, & lawsuit

July 5, 2022 / Professor Paul Knoepfler, Ph.D. / 11 Comments

Some unproven stem cell clinics like one called Giostar have multiple locations sprouting up. To me the concern with that spreading is the potential of multiplying risks to consumers. It can be hard to get a clear take on what these clinics are doing too. What’s in this article What is Giostar? | Giostar review |

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Did COVID derail FDA stem cell clinic plan?

June 30, 2022 / Professor Paul Knoepfler, Ph.D. / 2 Comments

The FDA stem cell clinic problem just continues to grow, while the agency has been oddly quiet in this space for more than a year. It’s been a major disappointment, particularly as in recent years FDA leadership had implied that bold action was coming. Their own words spiked expectations that the agency would tackle unproven

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Is embryonic stem cell research a target after Roe?

June 28, 2022 / Professor Paul Knoepfler, Ph.D. / 1 Comment

When I first started this blog back in 2010 the most contentious issue on the more political side of our field was federal funding for embryonic stem cell research. It was something you couldn’t take for granted. Some history on embryonic stem cell funding in the US There were times back then when funding of

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Paolo Macchiarini guilty in criminal stem cell case but does a Houdini again

June 17, 2022 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Dr. Paolo Macchiarini exemplifies how things can change quickly in the stem cell world and go from sky highs to deep lows. Stem cell rollercoasters Over the years, a few academic stem cell researchers as well as some operators in the unproven clinic sphere have had dizzying ups and downs. There’s John Kosolcharoen. His company

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Weekly reads: $1B Saudi anti-aging push, OCT4 necklace, cancer trial wows, coffee brain

June 12, 2022 / Professor Paul Knoepfler, Ph.D. / 1 Comment

I recently wrote about stem cell-related ideas for anti-aging and even cheating death, but there are of course other approaches including drugs like metformin. A new article outlines a massive research funding plan to tackle aging. Let’s start with that. Recommend reads including anti-aging Saudi Arabia plans to spend $1 billion a year discovering treatments to

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Fact-checking troubling R3 Stem Cell clinic chain

June 9, 2022 / Professor Paul Knoepfler, Ph.D. / 14 Comments

I’ve had concerns about an American unproven clinic firm called R3 Stem Cell for many years. They sell unproven stem cell-related “treatments” via dozens of affiliated locations. I put quotes around treatments because in my view there is no good evidence here for claims of treating numerous serious illnesses. The goal of today’s post is

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Fact-checking VSEL stem cells & VSEL treatment

June 7, 2022 / Professor Paul Knoepfler, Ph.D. / 6 Comments

A few people in the stem cell field keep arguing that adult pluripotent stem cells exist, including so-called “very small embryonic-like stem cells” or VSEL stem cells. These days the supposed cells are called VSELs or V-cells too. Only a handful of researchers have ever been able to report finding and studying these cells. Others

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Cheating death via regenerative medicine or stem cells?

June 1, 2022 / Professor Paul Knoepfler, Ph.D. / 7 Comments

How does one go about cheating death? As I get older, fighting aging seems more relevant. Having battled a potentially fatal cancer also gave me a taste of mortality. In biomedical research, it seems like living longer has become an obsession for some recently. Cheating death with cell therapies or other regenerative approaches? Could stem

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