Search Results for: weekly reads

Weekly reads: Beth Shapiro & de-extinction, mice with two dads, stem cell patches

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Beth Shapiro, De-extinction

Biologist and ancient DNA expert Beth Shapiro is becoming more well known for doing de-extinction research. Yet Shapiro used to be a de-extinction skeptic. Ten years ago she wrote “How to Clone a Mammoth.” In the book she mentioned serious challenges related to de-extinction. Now she is the CSO for a firm trying to make […]

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Weekly reads: NIH freeze even before RFK confirmation, FDA warnings, RP stem cell trial data

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NIH freeze

RFK isn’t even confirmed as HHS Secretary and things are going south already with an NIH freeze. What do I mean? NIH freeze could do lasting damage to biomedical research The Trump Administration has frozen many NIH processes including meetings such as study sections that evaluate grant proposals. No study sections means almost no new

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Weekly reads: FDA modernization, TFs on the brain, mortality timer, pluripotent trials

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FDA

How will things change at the FDA under the second Trump Administration? It’s a key question for our field but not easy to answer. Most likely there will be more instability at the agency. Some leaders, like of CDER, have already left. in my overall regenerative medicine predictions for 2025, I’ve included more predictions about

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Weekly reads: grow a spine, China clears MSCs, Denise Richards, stem cell soups

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Notochord, growing a spine.

If you tell a scientist that they should be growing a spine, they might take you literally. For instance, if you say this because you want a scientist to show some courage and speak out about something difficult, instead they might try to make an actual human spine in a lab. We’ll start there this

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Weekly reads: stem cell therapies that work, exosomes, H3.3 K27M, Joe Rogan

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stem cell therapy

How close are we to having new stem cell therapies that work? The field is nearly there on several fronts, but we shouldn’t get ahead of ourselves. Last week I noted the “soon” in a Nature News headline “Stem cells head to the clinic: treatments for cancer, diabetes and Parkinson’s disease could soon be here.”

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Weekly reads: intermittent fasting and stem cells, vet warning, blastemas

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intermittent fasting and stem cells

Intermittent fasting must be good for stem cells, right? It’s not so clear. Like many things in biology, intermittent fasting can have seemingly opposite effects. Before we get into that, the news of the week is that the FDA approved Mesoblast’s Ryoncil MSC drug for some cases of pediatric GvHD. This has sparked lively discussion.

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Weekly reads: aging cells, scientists relying on ChatGPT, anemone stem cells

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cellular aging

Do our aging cells necessitate that we age overall as people? Flipping it around, if we can stop or reverse enough cellular aging, will our overall aging be positively affected? It’s clear that people age very differently from each other and so do our cells and organs. Interestingly, intramurally in a sense the cells and

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Weekly reads: Scott Gottlieb v. RFK Jr., DNA typewriters, Arnold Caplan

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Peter-Marks-Scott-Gottlieb-FDA

Remember former Trump’s FDA Commissioner Scott Gottlieb? Gottlieb’s back in the news in an interesting way related to the upcoming second Trump administration. I just wrote about what to expect from new FDA Commissioner nominee Marty Makary. In that piece, I noted that Scott Gottlieb first came to lead the FDA after a record of

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Weekly reads: GIOSTAR stem cell clinic IND, cadaver marrow, NIH under Trump 2.0, tweets from a stem cell

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Giostar

What happens if unproven stem cell clinic firms like GIOSTAR start getting okays from the FDA to do clinical trials? On the one hand, it could reflect a positive trend of stem cell clinic firms working with the FDA and toward compliance. Having more robust data. However, I worry about some of these types of

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