October 24, 2020

The Niche

Knoepfler lab stem cell blog

Month: February 2016

2 min read

Medical News Today (MNT) published an article yesterday on a stem cell clinic in Mexico that caused a lot of concern because to many of us it came off as unbalanced and even promotional of the clinic. You can read my post from yesterday on this situation. In response, MNT has now revised their piece and included this statement: “When this article was first published on February 24th, we received criticism that it was promoting the World Stem Cells Clinic. Medical News Today always aim to provide balanced, reliable …Read More

4 min read

A new article by Honor Whiteman in Medical News Today (MNT) on a Mexico stem cell clinic really takes the prize so far in 2016 amongst media pieces that engage in stem cell hype. Update; Many on Twitter are calling for retraction of this MNT article. The MNT article entitled “Stem cell therapy: is the US missing a trick?” ends up overall being promotional for a Cancun stem cell clinic that is selling unproven stem cell “treatments” for a host of conditions including for kids …Read More

2 min read

Over the years some scientists including yours truly have expressed concerns about the possibility that mutations could crop up during the reprogramming process to make induced pluripotent stem cells (IPS cells or IPSC). How concerned should we be about IPS cell mutations? A cool new paper, Bhutani, et al, in Nature Communications from a team led by Jeanne Loring and Nicholas J. Schork presents data arguing against significant oncogenic mutations occurring during reprogramming to make IPSC. The authors summarize their findings this way: “Our results show a moderate …Read More

2 min read

Below is a my interview with an FDA spokesperson on the upcoming April public meeting on the four recent draft guidances related to the regulation of HCT/Ps, including stem cell treatments. This meeting and the draft guidances could have substantial impact on future regulatory frameworks for stem cell treatments so I thought it important to reach out to the FDA to clarify the process. PK: When the FDA issues draft guidances is it a standard approach to have a public meeting of the kind …Read More