Month: January 2018

Why we shouldn’t view the human embryo as a gizmo even in the CRISPR era

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My first job in science was as a lab technician at UCSD School of Medicine and a big part of that job was growing cells called HUVECs or human umbilical vein endothelial cells. We isolated and grew the HUVECs from umbilical cords that we retrieved from the maternity ward of the UCSD hospital, which first …

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Predatory clinics push stem cell secret society, deep state conspiracy theory

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Did you hear the one about the deep state FDA, big pharma stem cell conspiracy theory? This is the phony idea that the FDA, big pharma, and, heck, sometimes even certain academics (who could that be?) are plotting together as some kind of biomedical secret society or “deep state” to block promising stem cell therapies …

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Animated map video shows wildfire spread of US stem cell clinics lacking FDA approval

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There are now so many clinics selling non-FDA approved stem cell offerings across the U.S. that tens or hundreds of thousands of patients are at risk. How did we get here? What if we had a way of understanding how stem cell clinics spread across the U.S. in the first place? For example, an animated …

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Is monkey cloning a breakthrough or a bad idea?

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Is monkey cloning a good idea? We’re about to find out. A new Cell paper today reports the first cloning of monkeys via somatic cell nuclear transfer (SCNT), raising many questions. The paper from a team led by Qiang Sun is entitled, “Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer.” The highlight bullet points …

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Perspectives on high-profile stem cell retraction in the making from Kyoto University

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A researcher working at Kyoto University has reportedly engaged in misconduct leading to an institutional request for retraction of a paper from the journal Stem Cell Reports. The paper in question appears to have rather large-scale problems: “Kohei Yamamizu, a specially appointed assistant professor at the university’s Center for iPS Cell Research and Application, falsified all …

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CRISPR to make IPS cells: review of new Ding lab paper

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CRISPR and IPS cells are two of my favorite things so when they come together as in a cool, new paper from Sheng Ding’s lab, I’m excited to read it and curious as to what the scoop is. Since 2006-2007 when mouse and human reprogramming were first reported, many different methods have been explored to …

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Adverse event in IPS cell (ips細胞) trial for vision loss in Japan: initial perspectives

Takahashi-IPS-transplant

A team of researchers at RIKEN and Kobe City Medical Center reported at a press conference today a serious adverse event in a clinical trial participant receiving an induced pluripotent stem cell (IPS cell)-based therapy for vision loss. According to Japan Times and Yahoo! Japan (in Japanese), the patient in question in the IPS cell …

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Florida bill aims to “crack down” on state’s for-profit stem cell clinics

Stem-cells-Florida-California-

Florida is a hot mess on the for-profit stem cell clinic front. My own state of California isn’t much better and actually has a great number of clinics, but more problems are coming to light in Florida, at least at this point. Now WLRN reports that a legislator in Florida has proposed a new bill to try to …

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Some thoughts on taking risks in science & medicine

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Are you a risk-taker or do you do everything possible to avoid risks? Taking risks in science is necessary, but is there a wise way to take the risks you do? Science and medicine need a certain amount of risk and risk-takers to make transformative leaps forward. The risks in biomedical science can be conceptual …

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