Month: April 2018

Analysis: human immunity to Cas9 bigger #CRISPR therapeutic hurdle than off-targets?

Cas9-immunity-pre-print

Some in CRISPR-Cas9-land who are focused on potential future clinical applications are kind of rejoicing or at least sighing a breath of relief. This upbeat swing in the atmosphere (from investors especially) was sparked by retraction of that paper, the one initially reporting tons of supposed off-target CRISPR-Cas9 activity in mice, which turned out to be a “nothing …

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Can stem cells really fight aging & if so, how?

stem cells aging

If you want to fight aging, should you turn to stem cells? Does the idea of stem cells to battle getting old even make any sense? The answer is, “it depends.” It’s a really interesting area conceptually and technically for stem cells. A theory. There is evidence that things that happen to our endogenous stem …

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Patient’s Powerful Story on Multiple sclerosis and Getting Experimental Stem Cells

Caroline-Wyatt

Multiple sclerosis (MS) can be an extremely debilitating disease that ultimately is fatal in some patients and reduces life expectancy and quality overall substantially. An MS patient named Caroline Wyatt, who works at the BBC, had the courage to open up in full detail on the BBC about having MS, her experience getting an experimental …

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