January 26, 2021

The Niche

Trusted stem cell blog & resources

Month: February 2019

4 min read

Who are the top stem cell and regenerative medicine influencers to follow on Twitter and elsewhere in 2019? Terrapin asked this kind of broad question to some within our community about 5 years ago and came up with a Top 50 list of stem cell influencers, which I like to joke I was “at the top of” because I was #50 and they listed us in reverse order. What about today and soon in the coming year in 2019? Who are the major regenerative medicine …Read More

4 min read

Something very strange just happened at the journal Nature related to what’s called Muse cells. Kudos to them for dealing with it quickly though. They published an unreviewed research “article” on controversial (perhaps non-existent) stem cells called “Muse cells” that was actually a paid advertisement. After I communicated with the Nature team eventually they ended up pulling down the ad/article as of today. How can a research article be an advertisement? I don’t think it should be possible. An “ad/article”? Of course, research journals run …Read More

5 min read

When the FDA has a major problem with something, it can issue a warning letter or more rarely it can file suit in court for an injunction against the particular party. The FDA has now done both of these things on different fronts with Beverly Hills stem cell clinic doctor and cosmetic surgeon, Dr. Mark Berman. Berman and his clinic partner, urologist Elliot Lander, run an adipose stem cell firm called California Stem Cell Treatment Center. This clinic seems effectively to also be the HQ …Read More

1 min read

What new papers and news in the stem cell sphere caught your eye? Here are some recent items that seem notable to me. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. This paper reports cellular reprogramming to insulin-producing cells in mice. They reprogrammed α-cells with Pdx1 and MafA proteins. ‘Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease’ in Nature Neuroscience. Using IPS cells for insights. “What open chromatin features predict pluripotency?” asked and answered by the authors of this review …Read More

3 min read

I keep a yearly hub of stem cell & regenerative medicine meetings here on The Niche. Below I’ve pasted the list for 2019, which continues to grow. If you don’t see yours listed, send me an email with the info including a link (knoepflerATucdavisDOTedu). These meeting listings are not endorsements and I try to make this list fairly comprehensive, but if you see a clearly predatory meeting, please email me and I’ll look into taking it off the list. 2019 stem cell and regenerative …Read More

5 min read

Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In this post I tackle each of these arguments in favor of leaving the door open to “CRISPR babies” with science-based counterarguments. I also raise larger risks to going down …Read More

4 min read

Historically, the main route of proposed healing via stem cell therapy was cell replacement. In this way of thinking the transplanted cells engrafted (took up home) in the patient’s tissue and replaced dead or diseased cells. However, interest continues to grow in other possible modes of healing by stem cells that don’t rely on cell replacement. In today’s post I cover 4 other possible mechanisms for stem cell therapy to aid health. Secreted factors An alternative, not mutually exclusive model to cell replacement is …Read More

3 min read

Swedish Medical Center in Seattle is now marketing regenerative medicine therapies including some things that in my view are not really scientifically proven to work including via an infomercial. This is part of a bigger trend where more legit medical centers have begun selling regenerative medicine “treatments” that are still being developed. Sometimes they even engage in questionable marketing of this stuff too. The latest entry here is unbelievable in some ways. In the above segment sponsored by Swedish Medical Center on a show …Read More