October 30, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: Neuralstem

6 min read

I invited Neuralstem CEO, Richard Garr, to do a Q&A interview and he kindly accepted. The interview provides some novel insights into this major biotech in the stem cell sector. 1. How is Neuralstem doing today? What programs are underway that you find particularly exciting?  Garr: Neuralstem is moving on all cylinders these days on both our cell therapy and small molecule clinical programs.  We have just completed all the transplantations of our phase two ALS patients, with the data lock coming early in …Read More

4 min read

This is Part 2 of my interview with ALS and stem cell advocate, Ted Harada. You can read Part 1 of my talk with Ted on where things stand today with ALS, the FDA, and the Ice Bucket Challenge. What’s your opinion of the “Right To Try” law in Colorado and the concept more generally? It seems to have the potential to speed innovation, but also put patients at risk. How will this be balanced out?  Ted: I am a strong advocate for Right …Read More

5 min read

Is Neuralstem flirting with noncompliance via a Right To Try Law in Colorado? Colorado is an independent-minded state. For example, it is one of only a few states including Washington State with legalized marijuana use. More recently, Colorado passed a new law supported by the ultra-conservative Goldwater Institute, the so-called Right To Try Law. This law allows patients to try experimental, unapproved medical interventions that have completed a Phase 1 clinical trial. Most Phase 1 drugs ultimately fail to be proven safe and effective and Phase …Read More

2 min read

What’s going on these days with biotech companies working on stem cell-based products? Geron’s and Advanced Cell Technology (ACT)’s FDA-approved trials presumably continue. As expected, no news yet. It’s too soon. Two important questions regarding both these companies are (1) did they apply for CIRM funding and (2) if so, how did the review process a couple days ago go for them as CIRM reviewed applications for the $50 million stem cell trials round? Four firms in total applied for this CIRM funding, but …Read More