So many things go wrong during the lead up to clinically-evident Alzheimer’s disease. This complex disease pathway has, in turn, led to a vast array of approaches to try to treat or prevent Alzheimer’s. Most of these efforts one way or another have something to do with the amyloid plaques and tangles that accumulate in the …
What’s more important than Woolly Mammoth de-extinction research in the stem cell arena? Only maybe a 10,000 other things. Still, the mammoth de-extinction efforts capture people’s attention much more than the average research story. Mammoth De-extinction update Is de-extinction only a pipette dream? This startup has a big, expensive plan to find out, Popular Science. …
Early during my postdoc I was primarily interested in the role of Myc genes both in cancer and in stem cells, work that later included embryonic stem cells. These cells are often called ES cells. At first I first started studying N-Myc in neural stem cells using a conditional knockout approach. However, soon after I was …
Weekly reads: embryonic stem cells, Parkinson’s, Alzheimer’s Read More »
Could stem cell Alzheimer’s Disease (AD) research provide a potential path to future treatment or preventative measures? The goal of today’s post is to provide a review of the state of the field in this area including possible approaches and challenges. You can watch a video covering the topic by Dr. Paul Knoepfler below on …
Anyone with a seemingly only semi-functional nervous system now post-election might be turning to science to help their brains bounce back. Here are some of the things I’ve been reading or hope to soon. In good news for the stem cell and regenerative medicine field, especially here in California, it looks like us California voters …
There’s nothing like stem cell good news and interesting publications to perk one up on a Monday. Enjoy. What recent papers have struck you as exciting? Novel stem cell-based cancer approaches (Part 1) It was exciting when Fate Therapeutics got the first induced pluripotent stem cell (IPSC) IND in the U.S. for their IPSC-derived natural killer cell …
Stem cell good news: novel cancer work, new CA bills, Alzheimer’s, & more pubs Read More »
A team at the University of Miami has launched a claimed first of its kind stem cell clinic trial for Alzheimer’s Disease (AD). The trial seems somewhat unique in using mesenchymal stem cells (MSC) for AD and is being run with biotech Longeveron. You can read more on the actual clinic trial including all the …
New Stem Cell Clinic Trial for Alzheimer’s: Perspectives & Questions Read More »
Below is an excerpt focused on Alzheimer’s Disease from my new book on stem cells. Stem Cells: An Insider’s Guide, which is targeted to a broad audience of people interested in stem cells. Alzheimer’s Disease (AD) is one of the most devastating illnesses. It destroys the brain, which shrinks over time (see image from Wikipedia …
Book Excerpt: Stem Cells for Alzheimer’s Disease–Are We There yet? Read More »
Alzheimer’s Disease (AD) is one of the most devastating illnesses that the human race has ever faced. It literally destroys the brain, which shrinks as a result over time (see image at left from Wikipedia). The toll of AD is not only measured in hundreds of billions of dollars in health care costs and millions …
Can stem cells be used to treat Alzheimer’s Disease? Read More »
UPDATE: I have added more discussion at the bottom about therapeutics and how regenerative medicine might work for Alzheimer’s Disease. Alzheimer’s Disease (AD) is the most common cause of dementia throughout the world, affecting 10s of millions of people. The cost to society is staggering and on a personal level for those of us who …
Exciting stem cell progress on Alzheimer’s Disease Read More »