Search Results for: cancer

Weekly reads: news, legos for stem cells, FDA, cancer, more

Legos for stem cells Fig 1b

I’ve been busy recently focusing more on grant and paper writing than reading papers on stem cells, but my piece on trying to de-extinct mammoths via cloning-like methods drew strong opinions on both sides. Recent news and resources on stem cells We’re still awaiting a verdict in the big California federal court case where the FDA is …

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Weekly reads including MSCs & cancer stem cells

cancer stem cells

One of my main interests is the relationship between stem cells and cancer as well as what makes cancer stem cells tick. This week I’ve chosen to highlight articles on the role of stem cells in cancer plus other interesting publications. Cancer pubs related to stem cells including on cancer stem cells Identification of cancer-related …

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Weekly reads: stem cells vs. viruses, prostate cancer, apoptotic cell niche function, more

Morinaga et al Nature 2021 Stem cells and hair loss

The paper of the week is An isoform of Dicer protects mammalian stem cells against multiple RNA viruses published in Science. The take-home from the abstract is that the data, “demonstrate that mammalian stem cells can protect themselves from some RNA viruses by expressing an alternatively spliced isoform of the enzyme Dicer called aviD, which potentiates …

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Recommended reads: Bik, FDA letter, gecko cancer model, David Baltimore on COVID origin

gecko cancer

What can a gecko possibly teach us about skin cancer? Read on. It’s fun when a week’s worth of science reading covers so much territory including COVID-19, geckos that get cancer, a research misconduct sleuth, an FDA letter, and more. Baltimore weighs in on COVID lab origin idea Caltech has a very interesting interview with …

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Weekly reads: cancer stem cells & other pubs plus a puzzler

kyu yum nature cancer stem cells niche

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is …

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

chen et al fig 1e nat comm 2021 phc1

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally …

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Weekly reads: oncodevelopmental factors, iPSC cancer vaccine, more

stem cell vaccine paper ouyang et al

One of my main research interests is in oncodevelopmental factors. These include factors that are important both for normal stem cell biology and development as well as driving cancer when misregulated. One example includes the MYC family of proto-oncogenes. When I was a postdoc I got especially interested in trying to understand the normal role …

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Bluebird bio sickle cell gene therapy trial halted on cancer worry

bluebird bio, sickle cell gene therapy

Recently I was going through a list I’m updating of regenerative medicine biotech companies including Bluebird bio. Now just a few days later the world seems turned upside down for the firm and maybe to some degree for other companies doing related work. Bluebird bio blues: 2 trial participants get cancer News broke today that …

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Recommended reads: pluripotent stem cells, neural crest, cancer, more

pluripotent stem cell, neural crest cells

There has been quite a lot of pubs on research on pluripotent stem cells published lately. These include some more surprising findings such as a potential role for pluripotency-related programming in neural crest development. Here the week’s recommended reads. Neural Crest research: ties to factors involved in pluripotent stem cells Science, Reactivation of the pluripotency …

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