The best talk today was the keynote address by Dr. George Daley focused mostly on iPS cells. Dr. Daley is one of the world’s experts on iPS cells and pluripotent stem cells more generally. He covered many interesting elements of the iPS cell field including the genetic mutations that seem to occur during the reprogramming procedure. Epigenomic changes. Ways to integrate gene therapy and cell therapy approaches that are very exciting. However, he also asked a cautionary question: How long will it take to …Read More
Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In this post I tackle each of these arguments in favor of leaving the door open to “CRISPR babies” with science-based counterarguments. I also raise larger risks to going down …Read More
George Daley stem cell field SWAT analysis. He argues that the biggest threats to the stem cell field are premature and illegitimate clinical applications. He stresses need for innovation including by surgeons but cautions strongly against rushing therapies.
Trying to make a CRISPR baby any time soon would be a really bad idea. How bad? Last December 3rd I penned a piece for STAT News arguing for a moratorium on the heritable use of CRISPR in humans. This potential future, radical application of “gene editing” is now often colloquially referred to as “CRISPR babies”. Read that piece for the reasons behind my thinking and the risks involved in leaving the door open to using CRISPR to make people. Of course, this was …Read More