Search Results for: single-cell

Recommended reads: Single-cell work, COVID twin study, more

single cell analysis neural stem cells

Sometimes it seems like a theme spontaneously emerges in pubs that I want to read for a given week like the set of single-cell analysis papers but there are diverse, other items including a striking day-night brain stem cell cycle paper and an interesting piece on identical twins who got COVID. What are you reading …

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Recent stem cell pubs & news: reprogramming, chromatin, single-cell, Astellas, & more

stem-cell-news-pigs-organ-transplants

What new papers and news in the stem cell sphere caught your eye? Here are some recent items that seem notable to me. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. This paper reports cellular reprogramming to insulin-producing cells in mice. They reprogrammed α-cells with Pdx1 and MafA proteins. ‘Mitophagy inhibits amyloid-β and tau pathology and reverses …

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Recommended reads: Dux, 3D printed ear brings Vacanti mouse to mind, AMD, more

Vacanti Mouse

Eight years ago two new Nature papers broke on the scene reporting supposed STAP cells with one of the senior authors, Charles Vacanti of Harvard, most well known previously for making the so-called “Vacanti mouse” along with his brother Joseph. The Vacanti mouse had a bioengineered human ear growing on its back. While STAP cells …

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Recommended reads: engineered niche, ALS, SCOTS trial, human genome “done”

SCOTS trial

David Weinberg over at Science-Based Medicine has his part two of a deep dive into the so-called SCOTS trial, which is a non-traditional pay-for-play study. I highly recommend it. SCOTS trial under the magnifying glass In this piece, Weinberg provides interesting background on the two people running SCOTS. I’ve had many concerns about the SCOTS …

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Weekly reads: Google, stem cells & MS, VSELs, ‘hairy’ organoids, MYC

stem cells differentiating into neurons and glia

It’s been quite a ride doing this blog on stem cells and other technologies for more than a dozen years. So far it seems like I’ll keep it going. A large part of the reason is because of people needing good information about our field. Those people include scientists and physicians but also many in …

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Stem cell reads: regeneration, 8C, MYC, CRISPR babies

wound healing stem cells

Another busy week including on the grant writing treadmill or should I say Mobius strip, but I’m always on the lookout for new reading and this week a lot popped up on regeneration. Also, a paper on healing and scarring. I regularly write about stem cell journals. For a long time, it seems like Cell Stem …

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Recommended reads: senolytics, cow iPS cells, big CIRM royalty

Senolytics Steve Horvath

When we hear the word senile we might think stereotypically of an older person who has cognitive impairment, but some argue that senility can apply to cells too as they age and that such cells can be targeted by drugs called senolytics. Unfortunately, the supplements industry has picked up on this idea to sell iffy …

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Weekly reads: hydra heads, iblastoids, new 8-year grants

Grant writers handbook, grants cartoon

What if you could get 8-year grants to do whatever biomedical research you wanted? This sounds like a dream for many of us in the life sciences, but the first news item this week is all about such a potential new funding approach. The item especially caught my eye as I’m going to be doing …

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Weekly reads: R01 grant trends, DPPA4, adult human neurogenesis debate

NIH R01 grant trends

Great ideas and talented scientists are not enough as biomedical research needs funding and here in the U.S. that means having R01 grant success. The trends since 1995 are slowly heading the wrong way. The average age of getting your first R01 grant keeps getting older. There is also still a bit of a possible …

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