Search Results for: synthetic embryos

New lab-grown blastoids are strikingly similar to human embryos

blastoids nature paper figure 2

A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the …

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Papers on artificial embryos and muscle stem cells

Beccari-et-al-Nature-2018-pub-Fig-1a

If you are sick of the general news lately, I recommend turning to the wonder of cool science like the thought-provoking data in the duo of new stem cell pubs discussed below including on artificial embryos. Synthetic embryos A team led by Alfonso Martinez-Arias reports new findings in their Nature letter in the growing area …

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Doubts raised on key points of Nature paper on CRISPR gene editing of human embryos

Egli-Mitalipov-preprint

Is it possible that CRISPR gene editing actually didn’t happen in many of the human embryos in that big Nature paper that made such news a couple weeks back? Some doubts have emerged that call the main conclusions of the paper into question and argue that more definitive studies are needed to be sure. An …

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When does a human embryo model become the real thing & other tough questions for a new field

human embryo model mukul tewary sm

A human embryo model is a laboratory-produced collection of living cells that has some key things in common with real human embryos. They are made from pluripotent stem cells, which include embryonic stem cells and induced pluripotent stem cells or iPS cells. This research is both exciting and ethically complicated, raising some difficult questions. Embryo …

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Recommended reads: stem cell pubs plus science news

Fairchild-et-al-Scientific-Reports-2019-part-of-Fig.-2

When it comes to coverage of stem cell research in the media, science news can both be cool, but also surprising. Some of the more interesting publications don’t always draw news coverage too. This post is a list of recent notable pubs and news. First some pubs. How good are human brain organoids at modeling …

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Stem cell news update: the good, the bad, & the weird

embryo-model-legos-1

With stem cells there’s always all kinds of developments and news every week or even every day. Here is an assortment in no particular order of some of the latest news including some across the spectrum including weird and sometimes stuff. The linked phrases are often the actual headlines of the media pieces. New CIRM …

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Risks rise as ISSCR drops strict 14-day rule on human embryo growth in the lab

mouse embryos grown outside the lab

Something called the 14-day rule on growing human embryos in the lab helped keep a tough question in check for a long time: when is it ethically wrong or just practically unwise to continue growing a human embryo for research? There is no good answer based on science or anything else. ISSCR moves beyond strict …

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Levrier guest post on CRISPR Consensus Meeting – “we all must get involved in this debate”

Guillaume-Levrier

By Guillaume Levrier Human germline editing has been done before. It will be done again in the future, as it is relatively easy to perform. No mechanism with the de facto ability to prevent it from being organized has yet been designed, let alone implemented. But the fact that germline editing has, can, and will …

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The Hope of CRISPRcon: Year 2, Guest Post by Anna Everette

Anna-Everette

By Anna Everette The title of this article is partially borrowed from a fascinating Lightning Presentation delivered by John Doench of Broad Institute at CRISPRcon this year. In his talk, Mr. Doench pointed out how we’ve been looking up to this promising technology for a while now, hoping it will deliver the anticipated results (see …

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New chat with George Church on CRISPR’ing people, Zika, weapons, & more

George-Church

I talked last year about human genetic modification by CRISPR with George Church a year ago. Now we’ve followed up with a long chat on this topic going into much more detail and with questions on recent developments. Each question is listed numerically and then there is a back and forth on that question with George …

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