Search Results for: totipotent

Multipotent & totipotent vs pluripotent stem cells

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

What’s the difference between multipotent stem cells, totipotent stem cells, and pluripotent stem cells? The goal of today’s post is to help you learn and be clear on the differences. What’s in this article Definition of stem cells |Totipotent vs pluripotent stem cells | Pluripotent stem cells | Multipotent stem cells | The best kind of stem …

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What are totipotent stem cells & what can they do?

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Sometimes patients or my students ask me, “What are the best stem cells?” what information are they looking for? I think they often are looking for the most powerful stem cells so perhaps they should be asking, “What are totipotent stem cells?” Other times it seems what patients specifically want to know is what might …

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What are adult stem cells & their clinical applications?

mesenchymal cells

When someone uses the term “adult stem cells” you might think that simply means stem cells from adults. However, it’s not that simple. The goal of today’s post is to help you get all the key facts about adult stem cells. This includes the different types of adult stem cells and their clinical potential. What …

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

chen et al fig 1e nat comm 2021 phc1

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally …

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Autologous stem cell transplant vs allogeneic: all you need to know

autologous vs allogeneic

There are many ways to classify different stem cells including yours versus someone else’s cells, or in a clinical sense what we call an allogeneic versus autologous stem cell transplant. This post is focused on the difference between allogeneic (someone else’s cells) and autologous (your own) stem cell injections. As a stem cell biologist I …

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What is a teratoma? Research & treatment

What is a teratoma? human stem cell teratoma knoepfler lab sm

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma? Teratomas are germ cell tumors. What this means is that the cells …

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Haruko Obokata (小保方 晴子) website posts dubious STAP cell validation data

STAP-cell-Obokata-2016

Haruko Obokata is most well-known for her role as first author of the now retracted two STAP cell Nature papers. These manuscripts claimed to have made pluripotent and even totipotent stem cells simply by stressing cells out with acid treatment or in other ways. Nobody else could get this method to work to create the so-called …

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6 recent stem cell good news stories including on liver disease

IPSC-array

Ready for some stem cell good news? It can be difficult at times in a cutting edge field like stem cells in terms of keeping upbeat about hopes of rapid translation to help patients with real, proven therapies. It takes a long time, money, dedication, and even a bit of luck for the researchers and …

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STAP Cell Update: STAP-like paper, Real Origin of STAP cells

electric-iPSC

The STAP cell mess that began in January of this year has in some ways quieted down. In a broader sense, I believe that STAP is now and will be in the future viewed as a scandal that revealed some less than ideal aspects to the world of biomedical science and publishing. Where does this …

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RIKEN fails to reproduce STAP, big CDB shake up expected

STAP-stem-cells

Nikkei is reporting that the RIKEN internal attempt to replicate so-called STAP (acid bath) cells has failed. Update: apparently, although RIKEN calls the efforts preliminary, the team tried to make STAP an amazing 22 times and 22 times it failed. The rumors for weeks in the stem cell gapevine that RIKEN itself could not get …

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