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Weekly reads: BioViva & life-extension clinic, RMATs, universal cells

May 14, 2023 / Professor Paul Knoepfler, Ph.D. / 2 Comments

BioViva CEO Liz Parrish in YouTube video.

I’ve written before about Liz Parrish and her life-extension firm BioViva. Now they appear to have connections with another entity called Integrated Health Systems or IHS, according to a new Wired article. Some of what is going on with IHS and maybe BioViva in Mexico seems extremely risky to me. BioViva, Parrish, and Integrated Health Systems The […]

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Clade Therapeutics pursues universal cells for cancer therapy

November 4, 2021 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Clade Therapeutics has been pursuing the idea of using gene-editing to make universally compatible cells. The potential here is big. What if you could make cloaked stem cells that could be used to produce cellular therapies that could be given to most patients without fear of immune rejection? Clade Therapeutics Boston Business Journal covers the

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Weekly reads: More good news on stem cells for diabetes, Panda stem cells, pricey longevity club

September 29, 2024 / Professor Paul Knoepfler, Ph.D. / 1 Comment

People often ask me what is the most promising new cell therapy and while it is difficult to choose just one, I often highlight the promise of stem cells for diabetes. Here in the U.S., early data from diabetes clinical trials by Vertex look encouraging. Other teams worldwide are also working in this space and

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Weekly reads: bat stem cells & viruses, Lineage Cell, He Jiankui visa

February 26, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

Occasionally when I write a post there is an angry reaction to it in the blog comments, which was the case for my recent fact-check of the LifeWave X39 patches. As you can see in that post, I didn’t find convincing data to either back up the claimed stem cell connection. In my opinion, there

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New research on CRISPR gene-editing in stem cells, infographic

September 24, 2020 / Mina Kim / Leave a Comment

As a pivotal advance in the gene-editing field and timeline, CRISPR continues to be utilized for research on stem cells and human diseases. Today, I will explain some of the most notable recent findings in the stem cell-CRISPR field. To start things off, I have also created an infographic that briefly explains what CRISPR-Cas9 is,

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Our bodies, not our cells?

October 24, 2016 / Professor Paul Knoepfler, Ph.D. / 15 Comments

Do we own our cells? Do we have some intrinsic right to them once they are outside our bodies? One of the arguments I hear most often from physicians at stem cell clinics and some clinic patients is that patients have an inherent right to ownership and almost unlimited use of their own stem cells, but over

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Yamanaka on making iPS cells from each patient: ‘in reality, we cannot do that’

November 12, 2012 / Professor Paul Knoepfler, Ph.D. / 1 Comment

One of the big issues related to using induced pluripotent stem (iPS) cells is cost. To make iPS cells from each patient for subsequent stem cell-based treatment would cost a fortune, by some estimates $200,000 or more per patient if done one-by-one. It could easily end up not being covered by insurances companies and Medicare,

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Some thoughts on life, death, and stem cells

August 26, 2012 / Professor Paul Knoepfler, Ph.D.

I know. I know. Scientists are not supposed to publicly talk about the question of when life begins and about death, but these are kind of important things to talk about and think about, don’t you think? I do. So here goes…. It’s been a very intense, crazy few weeks for me and for many

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The New Scientist goes after ES cells with strange opinion piece

October 22, 2011 / Professor Paul Knoepfler, Ph.D.

What the heck happened to The New Scientist? An anti-embryonic stem cell piece they just recently published was an exercise in weird, moral obfuscation. Quite a few scientists and policy makers are fairly regular readers of The New Scientist. They might start reconsidering how they want to spend that $99/year. Why not use it to

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