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STAP cells (stap細胞) are real deal says new Vacanti patent declaration

January 10, 2017 / Professor Paul Knoepfler, Ph.D. / 14 Comments

STAP is back? Really? No, I don’t believe so, but there’s an interesting development and twist on the STAP cell front. Just a few days ago on January 4, 2017 Dr. Charles Vacanti, the originator of the STAP cells concept, submitted a declaration to the USPTO affirming the belief that STAP cells are real and requesting that

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Finally, Vacanti’s side of STAP cell implosion

February 22, 2016 / Professor Paul Knoepfler, Ph.D. / 11 Comments

A great new piece in The New Yorker by Dana Goodyear, The Stress Test, gives us a window into Charles Vacanti’s side of the STAP cell mess and includes recent quotes from him. It’s a long, fascinating look inside of STAP, the tangled and ultimately tragic scientific implosion that created and then brought down two Nature

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STAP News From Harvard? Vacanti Stepping Down as Chair & Going on Sabbatical

August 11, 2014 / Professor Paul Knoepfler, Ph.D. / 5 Comments

What’s the deal with Brigham and Women’s Hospital or Harvard Medical School, where STAP cell senior author works, when it comes to the retracted STAP cell papers? I was just writing yesterday in part about how we haven’t really heard anything (news, statements, etc.) from those places about the whole STAP cell mess. In contrast, in Japan

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Ear-itating: Awesome John Oliver Invokes Vacanti Mouse While Blistering Dr. Oz

June 24, 2014 / Professor Paul Knoepfler, Ph.D. / 2 Comments

What is the Vacanti Mouse? Comedian John Oliver has an absolutely blistering segment (see below) on Dr. Oz in which he skewers the physician huckster. The video includes incredibly telling Oz testimony before Congress in which the celebrity doctor seems frankly pretty pathetic and cannot answer even simple questions about his selling of arguably snake oil on

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Reactions to New On-Line Vacanti Lab STAP Cell Protocol

March 20, 2014 / Professor Paul Knoepfler, Ph.D. / 26 Comments

The Vacanti Lab at Brigham and Women’s Hospital/Harvard Medical School has now posted online their own version of the STAP cell production protocol. The thing that first struck me most strongly about this published protocol is that it is not the same protocol reported in the Nature papers and it also is not the same

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Vacanti to Speak on STAP Cells at Harvard on April 1

March 17, 2014 / Professor Paul Knoepfler, Ph.D. / 8 Comments

Dr. Charles Vacanti is scheduled as a special guest speaker on April 1 at Brigham and Women’s Hospital. He’ll be speaking on STAP cells. See image below of the announcement. The title of his talk is “Tissue Engineering and STAP Cells”. It is part of the Brigham and Women’s “Leaders in Regenerative Medicine Seminar Series”. Online

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Interview with Charles Vacanti on STAP Cells: Link to Spore Stem Cells & More

February 2, 2014 / Professor Paul Knoepfler, Ph.D. / 8 Comments

The recent publication of two Nature papers by a team in part led by Dr. Charles Vacanti on acid treatment produced stem cells (so-called STAP stem cells) has been a blockbuster story in the stem cell field and has grabbed major global media attention as well. For background my review of the paper here and more thoughts here. Many

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Perspectives 10 years after STAP cells: the culture of science, misconduct, & hopes for progress

January 29, 2024 / Professor Paul Knoepfler, Ph.D. / 6 Comments

Exactly ten years ago today, on January 29, 2014, I wrote about two new Nature papers on so-called STAP cells. The papers claimed that stress alone could convert regular non-stem cells into some of the most powerful stem cells. More specifically, the authors claimed to make pluripotent stem cells similar to iPS cells this way.

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4th Obokata retraction after Harvard investigation: STAP saga finally over?

February 13, 2020 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

Retraction Watch broke the news that Haruko Obokata of the STAP cell train wreck now has a 4th paper retraction. The publication related to the controversial idea that adult tissues have pluripotent potential or actual pluripotent stem cells in them so it was kind of foundational for the debunked STAP cell idea. It also reminds

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