Intermittent fasting must be good for stem cells, right? It’s not so clear. Like many things in biology, intermittent fasting can have seemingly opposite effects. Before we get into that, the news of the week is that the FDA approved Mesoblast’s Ryoncil MSC drug for some cases of pediatric GvHD. This has sparked lively discussion. […]
Weekly reads: intermittent fasting and stem cells, vet warning, blastemas Read More »
In a landmark decision, today the FDA approved Ryoncil from Mesoblast for GvHD. This is the first time the FDA has approved a mescenchymal stromal/stem cell or MSC therapy of any kind. There have been many ups and downs for Mesoblast toward this approval of Ryoncil or remestemcel-L, an allogeneic marrow MSC product. See my
In landmark, FDA approves first MSC therapy, Mesoblast’s Ryoncil for GvHD Read More »
Toward the end of each year I make predictions for the stem cell and regenerative medicine field for the coming year. I’ve been doing this for more than a dozen years in various forms. In this post I’m looking at the (gene-edited, stemness enriched) tea leaves for 2025 for the regenerative arena. These predictions include
25 stem cell & regenerative medicine predictions for 2025 Read More »
What is a stem cell therapy? Does it have to include stem cells put into the body? Would you include a therapy that uses differentiated cells made from stem cells? I generally do use the term in that broader way. A similar question comes to mind: what is regenerative medicine? Should it include both cell
Weekly stem cell reads: HSCT, old embryo models, aging stem cells Read More »
QC Kinetix is a relatively new regenerative clinic brand in the U.S. selling unproven cell therapies. I see several specific red flags including a class action lawsuit. They report having 150+ locations, making it potentially the largest chain of unproven clinics in the U.S. Collectively, these clinics could be seeing tens of thousands of customers.
QC Kinetix review: concerns on huge regenerative clinic chain Read More »
I’ve written before about concerns related to longevity research hype from Harvard professor David Sinclair. The media often eats up statements about longevity from Sinclair and a few other scientists in that space. There is also endless coverage of the latest exploits of wealthy health influencer Bryan Johnson. For that reason it was refreshing to
Refreshing WSJ piece on longevity ‘guru’ David Sinclair Read More »
Do our aging cells necessitate that we age overall as people? Flipping it around, if we can stop or reverse enough cellular aging, will our overall aging be positively affected? It’s clear that people age very differently from each other and so do our cells and organs. Interestingly, intramurally in a sense the cells and
Weekly reads: aging cells, scientists relying on ChatGPT, anemone stem cells Read More »
What was the biggest upbeat regenerative medicine story of 2024? I have my own favorites but decided to run a poll. Just putting the poll together, it was evident that this year was unusually full of good and encouraging news. Diabetes and sickle cell regenerative medicine therapies In The Niche polling, so far Vertex Type
Positive regenerative medicine story of the year: diabetes & sickle cell were tops Read More »
The FDA recently warned Frontier Biologics, LLC, a Texas perinatal tissue manufacturer firm. Tallying the many FDA biologics warnings in 2024 It can sometimes feel like there are an uncountable number of unproven stem cell clinics However, the good news is that the FDA has been doing much more on this front in 2024. With
FDA warns Frontier Biologics as part of its more active trend Read More »
Remember former Trump’s FDA Commissioner Scott Gottlieb? Gottlieb’s back in the news in an interesting way related to the upcoming second Trump administration. I just wrote about what to expect from new FDA Commissioner nominee Marty Makary. In that piece, I noted that Scott Gottlieb first came to lead the FDA after a record of
Weekly reads: Scott Gottlieb v. RFK Jr., DNA typewriters, Arnold Caplan Read More »