November 25, 2020

The Niche

Knoepfler lab stem cell blog

Paul Knoepfler

Paul Knoepfler, Ph.D. is a Professor at UC Davis School of Medicine in Cell Biology and Human Anatomy. His lab does research on stem cells and cancer, especially from an epigenomic angle. He also has been working on policy and ethics matters for many years. The author of 3 books, he also has a popular TED talk on designer babies.
4 min read

After all this time writing on The Niche here since 2010, I still haven’t entirely resolved certain blogging dilemmas including when a patient discloses something. It’s kind of a jungle out there on the internet. What kinds of tough blogging dilemmas do I face? I’m just going to give you some examples of the more common ones in this post. Patient disclosures & accusations Privacy. One dilemma that still feels like it needs more concrete approaches on my end is when patients publicly disclose things …Read More

2 min read

Anyone with a seemingly only semi-functional nervous system now post-election might be turning to science to help their brains bounce back. Here are some of the things I’ve been reading or hope to soon. In good news for the stem cell and regenerative medicine field, especially here in California, it looks like us California voters approved billions more in funding for CIRM, our state stem cell agency. Alzheimer’s new directions FDA scientists appear to offer major endorsement of Biogen’s controversial Alzheimer’s treatment, STAT News. An …Read More

5 min read

Can hearts repair themselves via their own stem cells? Science evolves Sometimes what we scientists all know to be true turns out later on to be wrong and there are clear instances of this in the stem cell field. For example for decades the dogma was that the adult mammalian brain did not have stem cells, but now most researchers believe that the adult brain does have stem cells, although for humans this is still being debated. What we perceive as factual can change over time. Yamanaka …Read More

2 min read

It’s fitting, given the edginess over the election, that Halloween is falling only a few days before election day so here is a list of recommended stem cell reads for you to dive into some biomedical science. Liver buds from stem cells Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media, Scientific Reports. In a decade might we have liver transplants based on this technology? If so, it will probably be small structures that are like a …Read More