November 26, 2020

The Niche

Knoepfler lab stem cell blog

Paul Knoepfler

Paul Knoepfler, Ph.D. is a Professor at UC Davis School of Medicine in Cell Biology and Human Anatomy. His lab does research on stem cells and cancer, especially from an epigenomic angle. He also has been working on policy and ethics matters for many years. The author of 3 books, he also has a popular TED talk on designer babies.
1 min read

Some scientists, even on Halloween, might be relatively immune to the fear of things that nonetheless freak out many everyday normal people. Brains, powerful lasers, antibiotic resistant genetically-modified bacteria, potent viruses, radioactivity. The list goes on and on. Mutant cells and animals. DNA containing cancer-causing genes. So as Halloween approaches, what does scare the heck out of scientists? Here is my list of the top scariest Halloween costumes to freak the lab coats off of scientists. If you are a scientist you might want to …Read More

6 min read

Last week I wrote a long post detailing the troubling multimillion-dollar reverberations between the Duke autism program and a for-profit stem cell clinic in Panama called The Stem Cell Institute. The potential entanglements between the Duke group and the Panama clinic raise a bunch of questions and concerns. They center on questionable, unproven autism “treatments”. In Duke’s case, their own clinical trial showed there was no benefit, but they forging ahead anyway. Muddy waters This Duke-stem cell clinic situation is a prime example of …Read More

3 min read

Maybe we can use science as an escape from politics during the last week or so before the election? I hope so. Here are my weekly recommended reads. Several papers ended up relating to nucleus, cell and embryo size and space as well as chromatin, which is very interesting. Cell and chromatin biology pubs, media Vast Self-Renewal Potential of Human AGM Region HSCs Dramatically Declines in the Umbilical Cord Blood, Stem Cell Reports DUSP16 is a regulator of human hematopoietic stem and progenitor cells …Read More

2 min read

It’s usually a tossup as to whether my weekly reads skew more towards stem cells/regenerative medicine or cancer. Other times they are more enriched for genomics and epigenetics articles. Seeds of cancer in normal skin, Nature News & Views Engineering synthetic morphogen systems that can program multicellular patterning, Science. Pig fat can be used to grow jawbones for humans, Science Mag news piece. Pig fat stem cells can aid in jawbone growth. Here’s the original Science Translational Medicine research pub. Inherited myeloproliferative neoplasm risk …Read More