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Autologous stem cell transplant vs allogeneic: all you need to know

autologous vs allogeneic

There are many ways to classify different stem cells including yours versus someone else’s cells, or in a clinical sense what we call an allogeneic versus autologous stem cell transplant. This post is focused on the difference between allogeneic (someone else’s cells) and autologous (your own) stem cell injections. As a stem cell biologist I …

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Weekly reads: embryo pubs stir things up, organoids crying, & more

organoids tear glands sm

This was an unusual week in that three papers in a sense collided together related to embryo production and growth, raising new research possibilities but also serious ethical questions. New research: what is an embryo & what is not? The first two Nature papers reported generating the most realistic models of human embryos from scratch …

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New lab-grown blastoids are strikingly similar to human embryos

blastoids nature paper figure 2

A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the …

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Multipotent & totipotent vs pluripotent stem cells

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

What’s the difference between multipotent stem cells, totipotent stem cells, and pluripotent stem cells? The goal of today’s post is to help you learn and be clear on the differences. What’s in this article Definition of stem cells |Totipotent vs pluripotent stem cells | Pluripotent stem cells | Multipotent stem cells | The best kind of stem …

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Weekly reads: stem cells for spina bifida & diabetes trials, pubs

arthur the dog helps test stem cells for spina bifida

It’s always great when there’s good news in the stem cell field and a new trial of stem cells for spina bifida here at UC Davis School of Medicine is very encouraging. So I’ll lead off with this story. Stem cells for spina bifida This pioneering work is led by Drs. Diana Farmer and Aijun …

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FDA warns Joseph Mercola on COVID-19 claims

joseph mercola and unproven stem cells

Those of you following the arena of unproven stem cells might recognize the name Dr. Joseph Mercola. He’s a promoter of alternative medicine. Over the years his name has also popped related to the marketing of unproven stem cell offerings in various ways. Now the FDA has warned Joseph Mercola on what it says are unapproved …

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What are embryonic stem cells & where do they come from?

Knoepfler lab stem cells

What are embryonic stem cells and how are they obtained? My lab has been doing research on embryonic stem cells for more than 14 years. You’ve come to the right place for expert answers on these very intriguing cells. What’s in this article Where do embryonic stem cells come from? | SCNT or cloning stem cells …

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Weekly stem cell research reads: BAF, Polycomb, Fertility, More

jonathan hoggatt, Moderna, stem cell research

What might be most surprising about this week’s recommended stem cell research reads is there’s nothing about COVID-19 in here. There are, however, some really great papers. And we can expect more developments on the cellular medicine for COVID-19 front coming soon. Before I jump into the reads, if you haven’t already check out our …

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