There’s nothing quite like getting a new paper out as a scientist running a research lab so this week we can celebrate our new pediatric brain tumor study. I’ll start the weekly reads with that paper. Of course, getting new grants is amazing too but there’s more of a feel of completion after a paper …
Weekly reads: our new brain tumor paper, levitation, dear doctor, Japan, more Read More »
My lab’s new paper in Communications Biology focused on high-grade pediatric glioma that have mutant histone variant H3.3 and we did something fairly novel that we are calling reciprocal CRISPR. Kids with these tumors have a near zero survival rate within a few years of diagnosis so we as a field desperately need something new to give …
Reciprocal CRISPR gene editing in pediatric glioma: defining mechanisms & testing drugs Read More »
What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding …
OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads Read More »
For the 4th straight year I’m going to get my head shaved to support St. Baldrick’s in their mission to cure childhood cancer. St. Baldrick’s is a great charity that raises money specifically for pediatric cancer research in part via events at which “shavees” raise funds via pledges that they will get their heads shaved. …
How can baldness help cure kid’s cancer? St. Baldrick’s Read More »
Glioblastoma and other related malignant glioma tumors including diffuse intrinsic pontine glioma (DIPG) are some of the most devastating of all human cancers, and glioma stem cells may contribute to the lethality. You can see an image of a glioma (the white area in the brain scan) from Wikipedia above. These brain tumors usually kill …
Are glioma stem cells a path to better outcomes? Read More »