What’s it like living with cancer? Exactly two years ago today, I was lying in a hospital bed literally across the street from lab here at UC Davis. It seems unreal in a way, but painfully real it was and still is. On November 30, 2009, I had surgery for prostate cancer. Two years ago, […]
My 2 years living with cancer, what I learned from Steve Jobs Read More »
Should men get a PSA test for prostate cancer? The same federal panel that recommended that women in their 40s not get routine mammograms has now come forth with the statement that PSA testing men for detection of prostate cancer should be stopped. I think it is not that simple and I still believe in
Should men get a PSA test for prostate cancer? Yes, but….. Read More »
As some of you know, I had prostate cancer in 2009 and by the looks of the pathology report, it seemed like a bad one. Part of my own unique experience of being a cancer patient is that I also happen to be a cancer biologist. You might think this would be helpful, but really
What cancer has taught me 584 days into my battle Read More »
Yesterday I ran a cancer stem cells meeting here at UC Davis School of Medicine. We had some great speakers and over 150 participants including our outstanding keynote speaker, Dr. Jeremy Rich, Director of Stem Cell Research at the Cleveland Clinic. One of the ideas percolating through the meeting was that during cancer development, there
Cancer stem cells and iPS cells Read More »
Just how tumorigenic are iPS cells? The field really doesn’t know at this point. However, a steady stream of papers have raised red flag after red flag about genomic and epigenomic alterations/mutations that are linked to cancer. Of course, then there is the fact that all the genetic changes actually used to make reprogrammed cells
Secret Not so Secret Recipe for Safer iPS cells Read More »
Each year brings more evidence that what causes many cancers is a case of biological betrayal on the part of stem cells via cancer stem cells. I have blogged before about the potential for stem cell-based regenerative medicine therapies to aid cancer patients. I have also written before about my own experiences as a cancer
Cancer Stem Cells: a new target Read More »
What is Contagious cancer? Can one creature directly give another creature cancer? It appears so in dogs and that cancer is highly contagious. Contagious cancer When we think about transplants of cells, we think about hospitals and high-tech equipment used to give patients stem cells or other types of cells to help treat them for
Contagious cancer: the allograft your dog doesn’t want Read More »
There is a kind of invisible cultural wall between patients such as cancer patients and biomedical scientists like me, but this wall does not have to exist and indeed it is a negative wall as patients, scientists, doctors, agencies, and advocates can achieve far more together than apart. But the wall is surprisingly strong. Last
My Cancer: how I became an advocate too Read More »
Yesterday I wrote about how difficult it is to tell different cell lines apart, including normal stem cells and cancer stem cells, especially since some accumulate accumulate oncogenic mutations that may make them seem more similar. A new paper is coming out that makes this case on a genomic level. Tomorrow’s Cell Stem Cell edition
Devil in the details: small oncogenic lesions in iPS cells & ESC Read More »
Cancer is a class of diseases that are intimately linked to stem cells. In fact, I would go so far as to call some types of cancer cells and stem cells, cousins. This concept, of a tight relationship between stem and cancer cells, is under intense investigation but at the same time it is something
Disease Focus Series: Cancer Read More »