cancer

Weekend cell biology reads: Mesoblast COVID-19 deal, pubs

bergert cell stem cell 2020 cell mechanics sm

The COVID-19 pandemic is tearing through the country right as we are starting into the holiday season, but the wheels of science including cell biology keep going and we keep reading all the great work. What news or papers caught your eye? Here are some of the things I have on my list of reading. …

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Weekly reads: cats, COVID, CIRM, cancer stem cells, MS

diana farmer and aijun wang uc davis 1

There have been many other interesting scientific and specifically regenerative medicine developments and papers this past week including with CIRM and exciting CIRM funding to UC Davis so read on, but first a somewhat random question: are you more of a cat person or dog person? I’d say I’m both. But our big dog is …

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Regenerative reads: pig fat, cancer, organoids, more

Chen-et-al-STM-2020-7a-fat-stem-cells-bone-sm

It’s usually a tossup as to whether my weekly reads skew more towards stem cells/regenerative medicine or cancer. Other times they are more enriched for genomics and epigenetics articles. Seeds of cancer in normal skin, Nature News & Views Engineering synthetic morphogen systems that can program multicellular patterning, Science. Pig fat can be used to …

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Regenerative medicine recommended reads including $191 million to researcher

Mark-Pennesi-CRISPR-regenerative-medicine-eye

It’s notable how the FDA now considers gene-editing a kind of regenerative medicine. This means that various gene therapy products in development technically qualify as regenerative therapies. Ever since the agency began its rapidly growing regenerative medicine advanced therapy (RMAT) designation program, we’ve seen an increasing number of gene therapy biotechs and products qualify as …

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Recommended recent stem cell, peds cancer & CRISPR reads

dental-stem-cells

Here are some articles that look especially interesting on stem cells, cancer, and CRISPR. I was just at the SNO meeting in SFO on childhood brain tumors so those are on my mind more. Childhood cerebellar tumours mirror conserved fetal transcriptional programs (Nature) Childhood brain tumors “think” they are building organds in fetuses. H3.3 K27M depletion …

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Stem cell good news: novel cancer work, new CA bills, Alzheimer’s, & more pubs

stem-cells-alzheimers

There’s nothing like stem cell good news and interesting publications to perk one up on a Monday. Enjoy. What recent papers have struck you as exciting? Novel stem cell-based cancer approaches (Part 1) It was exciting when Fate Therapeutics got the first induced pluripotent stem cell (IPSC) IND in the U.S. for their IPSC-derived natural killer cell …

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Could Cancer Risk Claw CRISPR’s Potential? Some Balanced Perspectives

Cancer-CRISPR

Could potential associated cancer risks claw into CRISPR’s potential? The short answer from both previous and new data is that while CRISPR gene editing impacts the P53 pathway, which is involved in cancer along with having many other functions, this news is neither too surprising nor a fatal flaw, but some caution is warranted. CRISPR …

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Stem cell clinic experimenting on patients with unapproved genetically modified ‘cancer vaccine’?

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What if it seemed based on the public statements of its leader that a business was using an unapproved and unproven, genetically-modified, stem cell-based ‘cancer vaccine’ on patients? Is that possible? Sometimes I think I’ve seen and heard it all when it comes to companies marketing non-FDA approved, scientifically unproven stem cell ‘therapies’ to patients …

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Help research on kid’s fatal cancers via Alex’s Lemonade Stand Foundation

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The Knoepfler lab has formed a team to raise research funds to try to find new treatments and hopefully cures for kids facing a type of mostly fatal brain tumors. Here’s the team page. If you can give us a hand by joining the team or making a donation that’d be wonderful. Any help would be appreciated. …

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Six questions as FDA takes new shot at stem cell clinics

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The FDA issued a historic statement today promising to more clearly define its regulatory policies on stem cell therapies and to take strong action on some stem cell clinics that it views as “bad actors”. I’ve never the FDA use such clear-cut language before. I give big kudos to new FDA Commissioner Scott Gottlieb. It already …

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