The FDA issued a statement this week that there have been reports of new cases of blood cancer after patients received CAR-T therapies. The FDA specifically mentions T cell malignancies. New cancers in rare cases? In the announcement, FDA Investigating Serious Risk of T-cell Malignancy Following BCMA-Directed or CD19-Directed Autologous Chimeric Antigen Receptor (CAR) T cell […]
Some CAR-T may very rarely cause new cancers Read More »
The first time I heard CAR-T cells referred to as a regenerative medicine it made me stop and think. Are CAR-T therapies really a type of regenerative medicine? Generally, CAR-T cells are a designer immune cell therapy. They work by killing cancer cells and that’s what came to mind to me. I don’t tend to
What are CAR-T cells & are they regenerative medicine? Read More »
Not everything in biomedical science is a ground-breaking discovery or clinical game-changer, but CAR-T cell technology is a combination of both. CAR-T cell good news We have such good news in this new pub on long-term benefits: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells, Nature. Another recent CAR-T cell article, this one in Science,
Weekly reads: CAR-T cell good news, Califf fight, stem cells on lymph Read More »
My weekly roundups of biomedical news tend to focus on stem cells, but I read more broadly so it’s not just stem cells but also CAR-T cells and a lot more this week. CAR-T cells as senolytics? A team led by Scott Lowe has a new intriguing paper in Nature on using CAR-T cells to
Weekly roundup: CAR-T cells, exosomes, trout cloning Read More »