January 26, 2021

The Niche

Trusted stem cell blog & resources

dedifferentiation

8 min read

We often talk about stem cells but there are some pretty basic, important questions that often go unanswered like ‘where do stem cells come from?’ The Niche It’s a more complicated and interesting question than you might think, and some of the answers point to novel ways in which stem cells may be used to treat human diseases. Note that if you are looking for information in a language other than English, my stem cell outreach pages have key facts about stem cells in …Read More

2 min read

A team from the Salk Institute in La Jolla led by Inder Verma has reported dedifferentiation in a paper in Science some important findings that I believe make their paper in the top 10 as a candidate for paper of the year. The paper, entitled “Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice” makes striking findings. The authors show that mature neurons and astrocytes (incredibly specialized, “terminally differentiated” cells) can be dedifferentiated. This is groundbreaking because these types of cells, …Read More