exosomes Archives - Page 2 of 2

Mystery of wild sci-fi film ad for unproven exosomes: Liveyon?

January 15, 2020 June 6, 2022 / By Professor Paul Knoepfler, Ph.D. / 8 Comments

What’s Liveyon up to these days? A new, somewhat mysterious short film that serves as an advertisement for unproven exosomes has some of us scratching our heads. It seems to point to Liveyon. Can you guys as readers of The Niche help solve the puzzle of who’s behind this wild “cinematic commercial” and what the …

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20/20 vision? The Niche’s 20 stem cell & regenerative medicine predictions for 2020

January 2, 2020 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

Every year in December and early January I do a post predicting some key events for the stem cell and regenerative medicine field for the upcoming year and today’s post contains my predictions for 2020. You can see my past 2019 predictions along with my grades for them here. I gave myself a B+ for …

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FDA spike: clinic supplier Liveyon warning letter & 483s; notice on exosome harms

December 9, 2019 September 26, 2023 / By Professor Paul Knoepfler, Ph.D. / 13 Comments

Friday and Saturday showed a burst in FDA activity related to unproven stem cells and regenerative products including a warning letter to the unproven perinatal “stem cell” provider Liveyon. This was an unusual 48-hour period and a very good one for those who believe in science-based regenerative medicine but in my view a bad day …

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4 possible roles for stem cell therapy besides cell replacement

February 6, 2019 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 20 Comments

Historically, the main route of proposed healing via stem cell therapy was cell replacement. In this way of thinking the transplanted cells engrafted (took up home) in the patient’s tissue and replaced dead or diseased cells. However, interest continues to grow in other possible modes of healing by stem cells that don’t rely on cell …

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As exosome work advances, clinics pitch unproven therapies to patients

August 26, 2018 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 29 Comments

Time to sell exosome therapies to patients? No. Some stem cell clinics and related firms are looking for new ways to make profits and toward that goal a few have latched onto the legitimate buzz around exosome research. What are exosomes? Imagine if you could bubble up a pea-sized sphere off your skin full of …

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Why did Texas A&M ink big deal with stem cell clinic firm Celltex on exosomes?

February 8, 2018 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

The recent news that Texas A&M University has inked a full-blown deal with the direct-to-consumer stem cell clinic firm Celltex struck me as an unusual development. Recently we’ve seen more universities exploring the use of stem cells outside of the traditional FDA clinical trial process that is fundamentally based on an investigational new drug application (IND). Some …

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Review of Nature paper: stem cell exosomes on the brain and aging

August 14, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

Is there a stem cell connection between the brain and aging? Could a type of brain stem cell or the exosomes it secretes control whole body aging? A recent big Nature article from the lab of Dongcheng Cai argues an emphatic “Yes” to these questions, at least in mice. In the Zhang, et al paper, entitled …

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What are exosomes and can they be used for therapy?

March 2, 2016 February 11, 2022 / By Johnathon Anderson

What are stem cell exosomes? There’s been an explosion of interest in the biomedical world around a recently characterized cell-to-cell communication system that most cells use to talk to one another, including stem cells. In fact the first patient has been successfully treated in Germany with exosomes derived from mesenchymal stem cells for refractory graft …

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