August 13, 2020

The Niche

Knoepfler lab stem cell blog

human embryo research

4 min read

My first job in science was as a lab technician at UCSD School of Medicine and a big part of that job was growing cells called HUVECs or human umbilical vein endothelial cells. We isolated and grew the HUVECs from umbilical cords that we retrieved from the maternity ward of the UCSD hospital, which first entailed getting the placenta and attached umbilical cord as our starting material. Some people viewed this material as “gross”, but as a newbie scientist I was kind of in …Read More

2 min read

UK biologist Kathy Niakan has asked governmental permission to make GM human embryos using CRISPR. Earlier this year, a research team in China crossed a scientific line for the first time in history by using gene editing technology called CRISPR-Cas9 to make genetically modified (GM) human embryos. Other researchers around the world including now one in the UK according to Reuters have expressed interest in creating GM human embryos too as a means to learn more about early human development. In many countries around …Read More

3 min read

A lot has happened in the week since the first human embryo genetic modification paper was published by a team led by Junjiu Huang. There have been a number of new events just in the last few days. Jocelyn Kaiser over at SCIENCEINSIDER has a new piece reporting a couple important developments including that the journal that published the human embryo editing paper, Protein & Cell, has issued an editorial explaining the review process for the paper. They argue that the review was fast, but …Read More

4 min read

Last week was a big one for the life sciences in that we saw the milestone of the first ever published paper reporting human embryo genetic modification (see here and here). It was one of those situations where we knew it was coming, but it was still a jolt. Not surprisingly this event sparked intense discussion and even some arguments. Below are 4 areas of contention at this moment and some additional thoughts on them. I value diverse views so please weight in with comments. A big deal …Read More