human embryonic stem cells

New lab-grown blastoids are strikingly similar to human embryos

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A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the …

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ViaCyte Q&A: CRISPR Tx quick progress, ongoing diabetes trial, & more

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ViaCyte is one of the most exciting stem cell and regenerative medicine biotech companies so I like to try to check in with them regularly. Today’s post is my new interview with ViaCyte leader Paul Laikind on recent developments. We had a great chat about the science and how things are looking upbeat for the …

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Lorenz Studer on Day 1 #ISSCR2018: HESC-based therapies for Parkinson’s Disease

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One of the highlights of Day 1 of #ISSCR2018 for me so far was the talk by Lorenz Studer (Co-Founder of BlueRock) on the use of human embryonic stem cell (HESC)-derived dopamine neurons for Parkinson’s Disease. Note that for this post and if I have time any others on this meeting, they are probably going …

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UK Biologist Niakan Asks to Make GM Human Embryos For Research

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UK biologist Kathy Niakan has asked governmental permission to make GM human embryos using CRISPR. Earlier this year, a research team in China crossed a scientific line for the first time in history by using gene editing technology called CRISPR-Cas9 to make genetically modified (GM) human embryos. Other researchers around the world including now one …

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Supreme Court Rejection of WARF hESC Patent Challenge Discussion

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The challenge to the WARF/Jamie Thomson patents/IP on human embryonic stem cells (hESC) is at an end. The US Supreme Court declined to hear the case. Earlier, the USPTO had turned down the challenge leading to a winding road in the courts. What do you all think of this stem cell IP challenge and the …

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Ian Wilmut, Dolly’s dad, says dump hESC? What does this mean?

Ian-Wilmut

Sometimes a top scientist makes news with a quote on research and that happened with Ian Wilmut recently on stem cells. Move away from research on human ES cells (hESC) in favor of very new and still largely unclear trans-differentiation technology? I say, no way. But, Bradley Fikes of the North County Times has reported …

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CIRM funds $25 million for Geron trial, $38 million for basic biology

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CIRM announced two sets of awards today that both should make major impact including its first clinical trial via Geron and $38 million for 27 basic biology studies. First Clinical Trial. Today CIRM awarded $25 million to support Geron’s FDA-approved clinical trial for spinal cord injury. This is CIRM’s first award to a for-profit company …

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