October 26, 2020

The Niche

Knoepfler lab stem cell blog


5 min read

Many are  jumping on the bandwagon of trying stem cells for COVID-19 or testing other cellular therapies for the novel coronavirus disease, but there have been problems with either the rationales for the trials themselves or more often with how they portrayed. Sometimes there has even been outright hype. I’ve called this collective trend of promotion of scads of trials of cell therapies for COVID “throwing spaghetti at the wall”. Some may stick, but most probably won’t. If fact, there’s a reasonable possibility that …Read More

2 min read

Meet The Screamers. After being a scientist in one form or another for 30 years and blogging about stem cells and other science for more than 10 years, I’ve seen a lot of science hype. However, some science hype goes above and beyond the usual level to outright smack readers in the face. It almost hurts your brain or makes you want to scream “No!” We definitely see this kind of uber-hype in the stem cell field at times, but also in many other …Read More

3 min read

A firm called Kimera labs just received an untitled letter from the FDA. The firm has been supplying non-FDA-approved exosomes to various customers including at least one stem cell clinic without sparking any obvious action from the agency, but on April 10th that changed with the letter, which in my view is quite serious. What sparked it? My sense is that a major trigger was Kimera Labs being linked some weeks back to an experimental infusion of exosomes into a COVID19 patient. The letter …Read More

5 min read

I thought I’d take a look again into the world of stem cell supplements since it’s been a few years. What I found wasn’t a pretty picture. (Note that “supplements” here refer to things people can ingest to somehow supposedly help their stem cells, not “supplements” that us scientists add to the media we use to grow stem cells.) Supplements in general For context, I’m fairly skeptical of supplements in general unless one has a documented deficiency in something like iron or maybe (maybe …Read More