Research

Stem cell research.

Weekly reads: NAM dubs 3 stem cell researchers, kick the 2 buckets, stem cell homing

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Sally Temple, stem cell researchers

The National Academy of Medicine elected a cohort of new members including three stem cell researchers. It’s great to see our field and these great scientists get recognition. The new NAM stem cell researchers include Sally Temple, Connie Eaves, and Tippie MacKenzie. Here’s a little bit about each of them. Dr. Temple is a stem cell biologist […]

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Weekly stem cell reads: bat stem cells, brainier organoids, more

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bat stem cell

I’m working to send out a big grant on Tuesday so I’m busier than ever but a few stem cell and regenerative medicine stories caught my eye. I can’t write grants 24/7 without a few breaks although sometimes it feels like that’s what I’m doing. Bat stem cell derivation Pluripotent bat stem cells as a

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Weekly reads: stem cell activator, sleep & stem cells, clonal hematopoiesis

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stem cells macrophages, stem cell activator

When people find out that I’m a stem cell researcher, a common question is whether there’s something they can take that is a stem cell activator. I’ve written before about whether there are stem cell boosts that one can do to try to be healthier. Sleep, stem cell activator and clonality Mostly when I bring

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Recommended reads: stem cells for ALS treatment trial, epigenome editing, astronaut mutations, ‘3-person embryo’ DNA

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stem cells for ALS treatment

A new stem cells for ALS treatment trial represents a big step forward. It’s early days still but this trial shows feasibility and provides a helpful foundation for moving forward. It also highlights challenges. The work is from a team led by Clive Svendsen. Stem cells for ALS treatment trial Here’s the study. Transplantation of

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Paper sparks renewed interest in transdifferentiation & clinical potential

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transdifferentiation, iOPCS

There was a time when I thought transdifferentiation based approaches might quickly move into clinical trials. Then things kind of cooled off. We didn’t see many papers reporting methods to transdifferentiate cells. I still think that this technology, sometimes called direct reprogramming, has major potential. A new paper on making human brain cells this way got

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Weekly reads: CRISPR, FDA stem cell loss, pioneering AMD study, MS, Verve Therapeutics

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FDA stem cell policy flow chart.

The big news of the week was the big FDA stem cell in court by Judge Jesus Bernal here in California, who ruled in favor of a chain of stem cell clinics called Cell Surgical Network. The FDA had been seeking an injunction against the clinics. I believe the ruling was founded in part on

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Weekly reads: fibroblasts, gene-editing, Mitalipov, personhood, embryos

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NIH 3T3 fibroblasts ATCC

I have a soft spot for fibroblasts, perhaps because one of the first immortalized cell lines I ever grew was NIH3T3. These are mouse fibroblasts that have been immortalized. They are very useful for a variety of experiments. I used them to study an oncogene called E2A-PBX1. Experience with fibroblasts including 3T3s I was amazed

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Weekly stem cell reads: space, plagiarism, HIV, diabetes, more

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blood stem cell biology

I took a cross-country road trip earlier this month that was pretty amazing and barely thought about stem cell research for the first time in years. We did run across one stem cell clinic in Florida by accident. I’ll write about that trip soon, but first we have our weekly reads including some very cool

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