I’m a fan of iPS cells, but my lab has been concerned about the similarities between induced pluripotency and cancer formation for many years. We just now published a paper that directly addressed the similarities of cancer and iPS cell transcriptomes. These are cause for concern and need to be faced as we contemplate clinical […]
iPS cells are similar to cancer cells paper, part 2: unsettled reviewers Read More »
In a few hours I’m going to submit my current R01 proposal to my institutional grants office, which will then submit it to NIH as is required by NIH. I’m tired. My brain is tired. I have a cold. I’ve read the grant a hundred times at least. I’ve had colleagues read it. I’ve taken
My R01 is due in a few hours, what’s on my mind besides ice cream? Read More »
There are at least 6 stem cell meetings this month. Wow. Check out the full list on our new Stem Cell Meeting page.
October is a rocking month for stem cell meetings Read More »
My lab just published a somewhat provocative paper (still in unproofed form at this point) arguing that iPS cells are very similar in some ways to cancer cells. How did we get to that conclusion (discussed in this post today, part 1 of the story) and what’s the back story on this paper (discussed in a later
iPS cells are similar to cancer cells: part 1 of discussion of new paper Read More »
Yesterday I managed to get to see a fabulous talk by Dr. Edison Liu, President and CEO of The Jackson Laboratory in Maine. I was able to squeeze it in, in between working on my R01 proposal and preparing for teaching histo to the med students here at UC Davis Med School. Dr. Liu was
This morning the Internet here at UC Davis Medical Center was on and off down for a couple hours. You’d think we had suffered a complete electronic catastrophe of the kind on the new sci-fi show on NBC, Revolution by JJ Abrams, where nothing electronic works even if it is battery powered. Here it was
Why you are probably an Internet addict too Read More »
Yesterday I just did a post on Jaenisch’s very dense, interesting Cell paper on iPS cells, but understandably it still is confusing to many people. I think I’ve come up with a helpful analogy. Imagine you are on a plane (this is your fibroblast cell) and the pilot dies. You have to fly the jumbo jet
Jaenisch new Cell paper on iPS cells 2.0: a helpful, brief analogy Read More »
The iPS cell field has had a relatively quiet 2012 so far, but one recent paper has drawn particular attention in the last 10 days. I’m talking about the paper from Jaenisch’s lab on iPS cells in Cell. Quite a few people are excited, but also scratching their heads a bit as to what this
Jaenisch’s new, complicated iPS paper in Cell: what the heck does it all mean? Read More »
The Texas Tribune held a liveblog regarding Health & Human Services at festival they were sponsoring. A particularly testy, interesting exchange on stem cells occurred (see starting around 2:51PM) involving Andrea Ferrenz of Celltex and Dr. Leigh Turner of University of Minnesota as well as Texas State Rep. Rick Hardcastle and David Bales of Texans
Stem cell shootout at the Texas Trib Festival including Celltex Read More »
Last year, for the second year in a row, I handed out awards to the top players in the stem cell universe. There were the Knoepfler Lab 2011 Stem Cell Awards. If you read that post you can see the full spectrum of the awardees, which included Matt Bohrs for stem cell political cartoon of the
Knoepfler Blog Stem Cell Awards 2012: Real prizes, nominate your favorites! Read More »