January 20, 2021

The Niche

Trusted stem cell blog & resources

stromal vascular fraction (SVF)

5 min read

When people discuss “fat stem cells” they usually mean something called “stromal vascular fraction” or SVF. While references to fat or adipose stem cells can sometimes mean non-SVF materials, these days adipose SVF gets the most attention. But, does anyone have a clear picture of this biologic? Fortunately, it’s starting to come more into focus in recent years and I’ve updated this post in late 2020. What is Stromal Vascular Fraction or SVF?  |   What cells are in SVF?   |   What about MSCs …Read More

3 min read

The unproven stem cell clinic firm US Stem Cell Inc. is in a world of hurt. If a federal judge says you can no longer sell your key commercial offering, how do you survive as a company? US Stem probably has been thinking about that possibility for months. Still, it’s not yet clear where the company goes from here now that this has become a reality. Where do things stand looking ahead? There’s financial pressure. The company’s stock ($USRM) has been a penny stock …Read More

3 min read

In the latest blow to the unproven stem cell clinic industry, a California federal district court judge just granted class status to a lawsuit against the fat stem cell clinic Stemgenex. (update: Stemgenex has since filed for bankruptcy). What this means in practical terms is that the lawsuit alleging fraud in marketing by the clinic firm amongst other allegations will proceed and may have 100s of patients involved. Many of these people paid nearly $15K per treatment to the company. Presumably some customers got …Read More

4 min read

It’s been less than a year since the FDA sued for a permanent injunction against a major stem cell clinic firm in Florida, but there has been much back and forth in court filings in the lawsuit between them and the firm, US Stem Cell. Now the case is with the judge. My prediction remains that the feds will prevail, but it seems worthwhile to look at some of US Stem Cell’s arguments. Note as a sort of disclaimer that I’m not an attorney …Read More

2 min read

A big, fat elephant in “the room” of the commercial stem cell field today is something called stromal vascular fraction or SVF, made from human fat tissue or adipose. If you care at all about stem cells or the stem cell field more generally, you had better educate yourself on SVF. You can learn a lot more here and in my new book, Stem Cells: An Insider’s Guide where I extensively discuss SVF, talk about the protocol to make it, and include the nifty diagram …Read More

5 min read

The Cell Surgical Network is a large and growing group of affiliated stem cell clinics across the US. The Network providers use stromal vascular fraction (SVF) interventions for a host of conditions on a for-profit basis. Drs. Elliot Lander and Mark Berman lead the Network. They agreed to do a Q&A interview with me. Below is Part 1, which delves into the Network itself. Part 2 on SVF, the FDA, and issues of homologous use can be read here. Part 3 of this series is my reaction …Read More

2 min read

IntelliCell (SVFC) is a stem cell company that does cosmetic stem cell procedures. They’ve had a number of challenges of late including an FDA warning letter about a year ago and apparent financial issues manifesting in lawsuits. Now the company itself, perhaps trying to get ahead of the news, issued a press release (PR) saying they were inspected by the FDA for 3 weeks recently. A typical FDA visit lasts 2 weeks during which time the FDA inspects documents, procedures, and such. It is unclear …Read More

2 min read

It’s difficult to make it as a biotech company, I would say stem cell biotechs in general may have an even rougher time, and one such company,  Intellicell (Intellicell Biosciences, Inc), is showing a number of signs of distress in my opinion. An online financial tool predicts the probability of companies going bankrupt within the next 24 months. For Intellicell it estimates a greater than 96% chance of bankruptcy. By comparison another stem cell biotech, Stem Cells Inc., has a less than 1% change of going bankrupt. How accurate are …Read More

3 min read

If you ever had a really bad day, March 13, 2012 might have been just such a bad day for one Dr. Steven Victor, aka “Dr LookGood”, because he received an official warning letter from the FDA. Why? Dr. Victor, who reportedly greets each patient with the catch phrase “You look so much more beautiful than your picture”, is CEO of a stem cell company called IntelliCell Biosciences of NY, NY. It is a stem cell-related cosmetic clinic that some celebrities fancy. The FDA says in its letter that …Read More