Search Results for: advanced cell technology

Fountain Life update: lawsuit by doc, high performance aging, Celularity trial plan

Fountain Life

A New Rochelle doctor has filed suit against the healthcare clinic firm Fountain Life alleging fraud. Now seems like a good time for an update on the firm. Peter Diamandis along with Bob Hariri, life coach Tony Robbins, and surgeon William Kapp founded Fountain Life, an early detection-focused healthcare company. Are they also a longevity firm? To …

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Weekly reads: artificial wombs, mice with rat brains, Neuralink

artificial wombs

It feels like we are marching towards a future in which key aspects of human reproduction, including the use of artificial wombs, could be substantially different than for most of history. The FDA is considering allowing a clinical trial for use of artificial wombs in people. Human trials of artificial wombs could start soon. Here’s …

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Weekly reads: stembryos or human embryo models, new Macchiarini sentence

stembryos, embryo models Monash

Researchers have been making stem cell-based embryo models for years now and a few folks have taken to calling these “stembryos.” Other names like gastruloids and blastoids are sometimes used too. “Embryo models” might be the simplest and best name. The embryo model research has advanced relatively quickly from very basic, not very organized structures …

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Grading my 2022 regenerative medicine predictions

stem-cell-crystal-ball-300x3001

It’s that time of year again when I grade my previous year’s predictions for the stem cell & regenerative medicine space. Overall, I did better than a typical year. I give the 2022 predictions an A- overall. This exercise can be kind of fun but also humbling. For example, I tend to be too optimistic …

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If you lost a loved one, could you turn to human cloning?

Human-cloning

One of the most interesting parts of running a website like The Niche is that reader’s questions can sometimes be so striking including recent ones on human cloning. They got me thinking about cloning again. Human cloning & loss of a loved one: things to consider Several readers have recently asked about whether human cloning …

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Dissecting that Neanderthal brain organoids Science pub

neanderthal human brain organoids

Organoids and especially brain organoids, which are made from pluripotent stem cells, are one of the most interesting developmental biology technologies of the last half a dozen or so years. Still some folks can’t help but get carried away when thinking about brain organoids it seems. A new Science paper from a team led by …

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Perspectives on Biohackers and DIY CRISPR

biohackers series sm

How should we view biohackers and their DIY use of CRISPR outside of the traditional industry or academic lab environment? Introduction to “Biohackers” and DIY CRISPR Who are biohackers exactly? They are people who “hack” their own biology by transforming their bodies through the insertion of technology or modification of their DNA. More rarely, biohackers …

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Authors on The Niche

Paul-Knoepfler

The Niche has had many authors over the years, focusing on expertise in the biomedical arena and in particular related to stem cells. I’ve invited many authorities in particular areas to write posts. Over the years I’ve written probably 99+% of the posts here on The Niche, but we’ve also had some great guest authors …

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Updated FDA granted RMAT List (85)

FDA-RMAT

Today’s post includes a list of firms/products that have self-reported that they have received FDA regenerative medicine advanced therapy designation or RMAT. Sometimes people call these “r mat” with a space. As of December 12, 2023 there are 85 RMATs in the public domain. I also include FDA data on RMAT submissions via an FDA RMAT resource …

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Chat with Michael Werner of ARM on Cures Act regenerative medicine provisions

Michael-Werner-Pic

One of the hottest topics in the world of stem cells this year has been the REGROW ACT and at a larger level the movement for changes in FDA oversight of investigational regenerative medicine therapies (see my past posts on it here), so the related provisions in the 21st Century Cures Act are stirring much …

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