Search Results for: stem cells for ms

Doug Melton Betatrophin Discovery Points to Future Diabetes Treatment?

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UPDATE: Unfortunately the Betatrophin paper discussed here originally back in 2013 has now largely been proven to have come to incorrect conclusions (for more read this). Today Harvard Stem Cell Institute (HSCI) reported the discovery, in a paper in Cell by Harvard Professor Doug Melton, of a powerful new hormone called Betatrophin that can stimulate […]

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What is Betatrophin & why is Harvard so excited about it?

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Harvard Stem Cell Institute (HSCI) is making a big announcement today about stems, the biggest they say in their almost decade-long existence. Last night I speculated/predicted some possible announcements. Today I’m betting they will announce the discovery of a novel factor called Betatrophin. More on Betatrophin in a minute, but first why do I think

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As iPS cell studies in humans approach, accessible relevant pre-clinical data remains minimal

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IPS cells, induced pluripotent stem cells, Knoepfler lab, stained for TRA-1-60, an ES cell marker., where do stem cells come from?

When are iPS cell-based therapies ready to be tested in actual people? It’s the million or perhaps even billion dollar question of today in the stem cell field. I realize that perhaps it is also a dangerous question, politically-speaking, for me to ask in a public forum, but patient lives as well as potentially the

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Transdifferentiation or direct reprogramming of fibroblasts to oligodendrocyte progenitors

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Back-to-back papers (here and here) in Nature Biotechnology report the transdifferentiation (now often simply referred to as “direct reprogramming”) of plain old fibroblasts into brain cells called oligodendrocyte progenitor cells (OPCs). OPCs are a remarkably useful kind of brain cell that generates myelin, which insulates nerves. OPCs are thought to have great therapeutic potential for

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Was sind Stammzellen?

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Was sind Stammzellen?  Der menschliche Körper enthält Hunderte von verschiedenen Zellarten, die für unsere tägliche Gesundheit wichtig sind. Diese Zellen sind verantwortlich für das tägliche Funktionieren unseres Körpers, wie das Schlagen des Herzes, das Denken des Gehirns, das Säubern unseres Blut durch die Nieren, das Ersetzen unsere Hautzellen, und so weiter. Die wichtige und einzigartige

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Interview with Arnold Caplan, Part 4: the FDA and the Future

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Today is part of 4 (the last) of my interview with Dr. Arnold Caplan, MSC godfather and guru. You can read parts 1-3 of the interview here, here, and here. In this post I focus on my discussion with Caplan on translation of stem cells to patients and the FDA. During our conversation we talked about some

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Great new Yamanaka interview on iPS cell safety, being a celebrity, & future plans

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The Asahi Shimbun just published a fun, intriguing interview with Shinya Yamanaka, the Nobel Laureate who first produce iPS cells. In the interview, Yamanaka says that the celebrity aspect of his new post-Nobel life has driven him to wear disguises when out running in public because he gets recognized so often. Yamanaka is also asked

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Interview with Regenerative Surgeon, Dr. Allan Wu

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Over the last few weeks, I have enjoyed talking with and interviewing Dr. Allan Wu, of The Morrow Institute on stem cell cosmetic procedures. I was impressed greatly by his talk at the World Stem Cell Summit last year. Dr. Wu is a fellowship trained Surgical Molecular Biologist with a background in Molecular Embryology and a board

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