This was an unusual week in that three papers in a sense collided together related to embryo production and growth, raising new research possibilities but also serious ethical questions. New research: what is an embryo & what is not? The first two Nature papers reported generating the most realistic models of human embryos from scratch […]
Weekly reads: embryo pubs stir things up, organoids crying, & more Read More »
A new word has been added to the lexicon of human stem cell research – blastoids, aka “blastocyst-like structures.” Unlike the familiar three-layered embryo that emerges during the third week of prenatal development, the earlier blastocyst resembles a fluid-filled soccer ball, with a smear of cells on the interior face destined to develop into the
New lab-grown blastoids are strikingly similar to human embryos Read More »
Sometimes change takes a very long time, but with brain organoids or advocating for better information for patients at Clinicaltrials.gov, after waiting you can see some interesting developments. These are two of the regenerative medicine stories of the week, along with some striking research papers. Clinicaltrials.gov Some of us have been advocating for improvements at
Regenerative reads: brain organoids, Clinicaltrials.gov change Read More »
Organoids and especially brain organoids, which are made from pluripotent stem cells, are one of the most interesting developmental biology technologies of the last half a dozen or so years. Still some folks can’t help but get carried away when thinking about brain organoids it seems. A new Science paper from a team led by
Dissecting that Neanderthal brain organoids Science pub Read More »
How much does platelet rich plasma or PRP injection cost? We might start by first talking about how to define PRP. PRP is an extract from blood enriched for platelet growth factors. There are many ways of making PRP and products are very heterogeneous. Some preps may contain actual platelets or fragments of platelets. These
How much does platelet rich plasma or PRP injection cost? Is it a good option? Read More »
During the week as I’m doing other stuff I keep my eyes open for interesting things to read, including over the weekend about stem cell research, COVID, CRISPR, and more for The Niche weekly recommended reads. This week a lot was going as we updated The Niche site to our new theme and format. I
Recommended reads: jobs, FDA letter, & The Niche new look Read More »
Today’s post announces the winner of the 2020 The Screamers Science Hype Award. Since this is the inaugural year for The Screamers, I’m just going to give out one main award: Overall Worst Science Hype. Science Hype Award to FDA Commissioner Stephen Hahn Remarkably, the winner of the overall The Screamers Award for Science Hype
2020 The Screamers Science Hype Award goes to Stephen Hahn Read More »
When my wife and I were expecting our first daughter way back in the nineties, we received a paper pamphlet about cord blood banking. Back then, I was a graduate student at UC San Diego School of Medicine working toward my Ph.D. in Molecular Pathology and my wife was in medical school at the time
Fact-checking, pros and cons of cord blood banking Read More »
Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma tumor? Teratomas are germ cell tumors. What this means is that the
What is a teratoma tumor? Research & treatment Read More »
The paper of the week reports using base-editing, a kind of gene-editing, to reverse mutations associated with rapid aging syndromes, generally called progeria, but there are a lot of other interesting pubs to recommend for reading this week. I go over it all in this post. Gene-editing to fight premature aging syndromes In vivo base
Weekly reads & paper of the week: gene-editing vs. aging Read More »