Search Results for: Shoukhrat Mitalipov

Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease

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Mitalipov-IPSC-paper

In a new, thought-provoking paper today in Nature, Shoukhrat Mitalipov and a multi-institutional team report a significant advance toward potential novel ways to treat mitochondrial diseases. What are these illnesses? Mitochondrial diseases are rare, but devastating disorders caused by genetic mutations. Today they are largely impossible to treat in meaningful ways other than palliative care. Some […]

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Review of Mitalipov Nature paper: cloned ES cells vs iPS cells

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NT-ESC

Just how good are human embryonic stem (ES) cells made by therapeutic cloning via nuclear transfer, with the successful technique first reported by the lab of Shoukhrat Mitalipov at OHSU last year? How do they compare to induced pluripotent stem (iPS) cells or traditional ES cells made from IVF embryos? A new paper in Nature directly tackles these

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Weekly reads: escape to New York, CRISPR baby patents, ISSCR guidelines, pubs

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the high line in manhattan

My to-read list this weekend includes a range of papers along with various news & media including a report of two US research groups aiming to get CRISPR baby patents. More on that below. At long last a trip + fun thing to do in NYC Last week I took my first trip in more

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Counterpoints to Lovell-Badge & Daley’s CRISPR baby rationales

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CRISPR-baby

Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In

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FDA chides US doc who genetically modified human embryo in reported 3-person IVF

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John-Zhang-with-3-person-IVF-baby

The FDA sent a stern letter today to Dr. John Zhang, PhD, MD, the physician who last year created a genetically modified human embryo in the U.S. and then exported it to Mexico where he self-reported creating a genetically modified baby boy. While the genetically modified baby created in Mexico was reportedly seemingly OK, it’s not clear

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20 Nominees for Stem Cell Person of the Year 2016 Award

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Stem-cell-person-of-the-year-award

I received a score of great nominations for the Stem Cell Person of the Year 2016 Award and have briefly described the twenty nominees below. The point of the award is to honor the top positive stem cell leader who specifically thinks outside the box and takes risks. I’ve started an on-line vote where you can vote once per day for

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