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Mesoblast gets FDA RMAT; List of 10 total designations so far

December 26, 2017 / Professor Paul Knoepfler, Ph.D. / 13 Comments

Australian stem cell biotech Mesoblast announced that it has received regenerative medicine advanced therapy (RMAT) designation from the U.S. FDA. This is very good news for the company and an encouraging development for the field. Interestingly, last month the FDA clarified that there is expanded RMAT designation that can include gene therapies too. At the Meeting […]

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Grading my twenty 2017 stem cell predictions

December 20, 2017 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Each year I make a list of predictions for the year to come for the stem cell and regenerative medicine field. Then about a year later I grade myself on how I did as that year winds down. Here’s how I did in 2016. For 2017, late in 2016 I made 20 stem cell predictions. Let’s

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Stem cell good news: Spinal Cord Injury Trial, CIRM, Grants, & More

October 2, 2017 / Professor Paul Knoepfler, Ph.D.

Stem cell good news time and more will be coming later this week. The stem cell and regenerative medicine world sometimes feels chaotic. Why? Because so much is going on both on the positive and negative sides of things. There is a whirlwind of activity and developments, and a tendency sometimes within our arena to

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2017 stem cell predictions: score card at 1/2-way point

June 18, 2017 / Professor Paul Knoepfler, Ph.D. / 1 Comment

In December of each year I make a list of stem cell predictions for the coming year, and I made 20 such predictions for 2017 so I’m wondering how I’m doing so far on these now that it’s June. Below is my work-in-progress scorecard for these so far. Positive news from Asterias on trial for stem cell-based

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Stem cells Sunday brunch of good news, fun links, & cool papers

May 21, 2017 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Enjoy! A Sunday brunch for the brain of science news, helpful links, and notable new papers including on stem cells. News and links CBER Director Focuses on Flexibility to Advance Regenerative Medicines Lab-Grown Blood Stem Cells Produced at Last Transplanted stem cells become eggs in sterile mice Maryland fund awards $8.5 million for stem cell research Positively good news from Asterias

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Upbeat prospects for some California clinical trial efforts from CIRM

May 1, 2017 / Professor Paul Knoepfler, Ph.D.

Over at the California Stem Cell Report, David Jensen is reporting on some good news from CIRM for California on the stem cell clinical trial front. Stem cell biotechs Asterias and Capricor have stem cell trials supported by 20+ million in CIRM funding each and have been hitting milestones. These trials are progressing and so far have good safety

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Good stem cell news on trials, FDA, cool new papers & more

January 31, 2017 / Professor Paul Knoepfler, Ph.D. / 2 Comments

In the whirlwind that is the stem cell and regenerative medicine world, there are many concerning things that need attention, but also good stuff happens too and this post focuses on the positive. The Asterias spinal cord injury clinical trial, a phase 1/2a trial called SCiStar, continues to make encouraging news with a clean safety profile

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Stem Cell Predictions for 2017

December 29, 2016 / Professor Paul Knoepfler, Ph.D. / 7 Comments

Each year I make a list of predictions for the stem cell and regenerative medicine field for the coming new year. Later in this post I list my top 20 stem cell predictions for 2017. In looking at my past predictions I realized this will now be my 7th year doing stem cell/regenerative medicine yearly predictions.

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Google Stem Cell News Stories: Perspectives

September 16, 2016 / Professor Paul Knoepfler, Ph.D. / 3 Comments

What does Google think (if Google does indeed think) are top 10 stem cell news stories right now? I took a screen shot below. Here are some thoughts on those stories. First, lung organoids are neat, but they have been grown before by several groups. Why is that the top story? I’d have to ask Google. Better

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Positive Stem Cell Developments in 2014

December 24, 2014 / Professor Paul Knoepfler, Ph.D. / 2 Comments

A lot has happened in 2014 in the stem cell and regenerative medicine field and so much of it has been good news so let’s focus on the positive. These positive developments are often the result of many years of creative, hard work by amazing teams of researchers. Here is my top 10 list of

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