Stem cell revolutionaries Drs. Shinya Yamanaka and John Gurdon have won the 2012 Nobel Prize for Physiology or Medicine. Gurdon cloned for the first animal, a frog, and Yamanaka produced induced pluripotent stem cells (iPSCs), a kind of stem cell with the power of pluripotency, but derived from ordinary non-stem cells. Gurdon’s work was based […]
Nobel Prize 2012 for stem cells to Yamanaka & Gurdon: why only 2? Read More »
As I was compiling a list of the upcoming stem cell meetings the other day I got to thinking about the different kinds of stem cell meetings and how diverse they are. Some didactic in a stodgy kind of way, while others are just as educational and instructive, but in a more enjoyable format. Some
Why you should go to the World Stem Cell Summit Read More »
I’m a fan of iPS cells, but my lab has been concerned about the similarities between induced pluripotency and cancer formation for many years. We just now published a paper that directly addressed the similarities of cancer and iPS cell transcriptomes. These are cause for concern and need to be faced as we contemplate clinical
iPS cells are similar to cancer cells paper, part 2: unsettled reviewers Read More »
In a few hours I’m going to submit my current R01 proposal to my institutional grants office, which will then submit it to NIH as is required by NIH. I’m tired. My brain is tired. I have a cold. I’ve read the grant a hundred times at least. I’ve had colleagues read it. I’ve taken
My R01 is due in a few hours, what’s on my mind besides ice cream? Read More »
Top stem cell meetings and conferences. If you want me to post your meeting, email me or post a comment (I’ll delete the comment and add the meeting to the main page). Meetings from 2012 can be found here. My listing of these meetings is not an endorsement of them, but is provided for informational
Stem Cell Meetings & Conferences 2013 Read More »
Did Celltex just get an FDA warning letter? I’m not sure. We may find out tomorrow as the FDA updates their public warning letter list early in the week. What’s Celltex? Celltex is that famous stem cell company in Sugarland, Texas that gave Guv Rick Perry stem cell transplants. It was inspected by the FDA
Did Celltex just get an FDA warning letter? Read More »
My lab just published a somewhat provocative paper (still in unproofed form at this point) arguing that iPS cells are very similar in some ways to cancer cells. How did we get to that conclusion (discussed in this post today, part 1 of the story) and what’s the back story on this paper (discussed in a later
iPS cells are similar to cancer cells: part 1 of discussion of new paper Read More »
Yesterday I managed to get to see a fabulous talk by Dr. Edison Liu, President and CEO of The Jackson Laboratory in Maine. I was able to squeeze it in, in between working on my R01 proposal and preparing for teaching histo to the med students here at UC Davis Med School. Dr. Liu was
Chronic obstructive pulmonary disease (COPD) is a relatively common, often debilitating illness, which has a major impact on the people of the world. In the U.S. alone, COPD costs the country almost $50 billion a year not to mention untold suffering. Most of us know someone who has COPD. COPD is an umbrella term that
Stem cells for COPD including emphysema: are we there yet? Read More »
Chromatin/Genomics/Transcription Tools ChIP grade antibodies MOTIF enrichment tools for DNA analysis GREAT (Stanford) CEAS HOMER MEME ENCODE Promoter Array On-line Analysis Online Tiling Array Analysis ChIP-Seq data on-line Analysis Plant Tools Transfac UC Davis Genome Center Methylation tools Yeast tools Fly ChIP-chip database General Science Tools Blast Search Genomic Blast Search ENSEMBL Blat Search
Handy BioMed Science Tools Read More »