A new paper is out from a team at The Salk lead by Joseph Ecker that the methylomes of many different human iPS cells. Their conclusion is that while iPS cells and ES cells are generally very similar in terms of the global portions of the genomes that are methylated, iPS cells exhibited hundreds of […]
iPS cells are not going to replace ES cells Read More »
Last night President Obama gave a state of the union speech. He seemed appropriately somber given the many issues facing the country. One issue of particular importance is the federal budget and the deficit. Will Obama strongly get behind biomedical research and request budget increases for 2011 for NIH and NSF? If not, then the
A sputnik moment for stem cells? Read More »
Can one creature directly give another creature cancer? It appears so in dogs and that cancer is highly contagious. When we think about transplants of cells, we think about hospitals and high-tech equipment used to give patients stem cells or other types of cells to help treat them for a disease. Generally cancer patients are
Contagious cancer: the allograft your dog doesn’t want Read More »
As we have blogged before, there are a host of different beliefs about embryonic stem cell research and about when life begins. This diversity of perspectives is sprinkled across the globe. Too often in the U.S. people take an ethnocentric view of this question, believing that everyone else should think the same as they do.
A perspective on U.S. embryonic stem cell research from Israel Read More »
There is a kind of invisible cultural wall between patients such as cancer patients and biomedical scientists like me, but this wall does not have to exist and indeed it is a negative wall as patients, scientists, doctors, agencies, and advocates can achieve far more together than apart. But the wall is surprisingly strong. Last
My Cancer: how I became an advocate too Read More »
In 2010 I blogged about the exciting finding that researchers could derive most blood cell types from stem cells. You can read more about that here. Here also is a video of Micky Bhatia discussing the findings: Mick Bhatia on turning skin cells into blood. Now comes a new paper (you can read it here) from
Is stem cell-derived blood on the horizon? Read More »
New California Governor, Jerry Brown, today proposed a 17% cut in funding for the UC System. Such a cut would be devastating to California at many levels including education, research, and competitiveness. The UC System is already under extraordinary stress from recent budget cuts that have inflicted serious injury upon the system. The new Governor’s
Jerry Brown vs. California Education and Research Read More »
Yesterday I wrote about how difficult it is to tell different cell lines apart, including normal stem cells and cancer stem cells, especially since some accumulate accumulate oncogenic mutations that may make them seem more similar. A new paper is coming out that makes this case on a genomic level. Tomorrow’s Cell Stem Cell edition
Devil in the details: small oncogenic lesions in iPS cells & ESC Read More »
What makes stem cells different? The stem cell field is faced with a dilemma as stem cells and some non-stem cells are sometimes too similar to tell apart. Even worse, stem cells and cancer cells are especially similar. If one focuses specifically on cancer stem cells (aka tumor initiating cells), the similarity between cancer stem
What makes stem cells different? Read More »
In this post I give my most interesting predictions about events in the stem cell field in 2011. Update: I’ve continuing doing predictions every year all the way through 2020 and intend to continue. See my 2012-2020 predictions here. Appeals court rules in favor of federally funded hESC research. This is more of a hope
Predictions for Stem Cells in 2011 Read More »