Search Results for: als

Why scientists must be advocates too: Jeff Sheehy

Jeff-Sheehy

CIRM Board Member, Jeff Sheehy, has a wonderful piece in Nature Medicine on why patient advocates play a critical role in decision making on research priorities (hat tip to Amy Adams who first blogged on Sheehy’s piece). Patient advocates bring a unique and valuable perspective to the table. Their role in guiding CIRM research funding …

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Disease Focus Series: Stem cells for HIV/AIDS

HIV-virus-lymphocyte

2020 update: This post from almost 10 years ago on the HIV pandemic and particularly the first paragraph ring differently in the context of the COVID-19 novel coronavirus pandemic. Over the last several years, there has been great concern about a possible flu pandemic around the world, but meanwhile the great pandemic of modern history, …

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Stem cells for Spinal Cord Injury update

spinal-cord-injury-MRI

The severe spinal cord injury sustained by Jockey Michael Martinez and the possibility (not realized) that he might be enrolled in Geron’s hESC-based spinal cord regenerative medicine trial, have drawn recent attention to spinal cord injury. Christopher and Dana Reeve (see foundation here) as well as Don C. Reed (see site here) were instrumental in bringing …

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Stem Cells in Wonderland

The-White-Rabbit-from-Alice-in-Wonderland

In Lewis Carroll’s masterpiece, Alice in Wonderland, there is a wonderful passage that came to mind as I read the latest response from the self-proclaimed ‘adult stem cell researchers’ suing the government to stop federally-funded ES cell research: “I don’t know what you mean by ‘glory,’ ” Alice said. Humpty Dumpty smiled contemptuously. “Of course you …

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Keep Your Stem Cells Away From BPA

Plastic-BPA

We live in a plastic world, full of BPA. Over the last 1/2 century, the proportion of our food and beverages that are consumed out of plastic containers has skyrocketed. Unfortunately, the concentrations of plastic-related chemicals in people around the world, even in remote corners, has gone up in parallel. I’ve written about avoiding plastic …

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Anonymous stem cell scientist frankly answers questions about the field

Anonymous-scientist-stem-cell-field

Here an anonymous stem cell scientist frankly answers questions about the field in an interview with me. Of course I have to ask you about the recent U.S. court ruling essentially declaring all federal funding of human ES cell work illegal. What’s your take on this? ANSWER: The ruling has so many flaws in it. …

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Parkinson’s Disease, promising new results on iPS cells

Parkinsons-Disease-stem-cells

UPDATE: A second recent study, this one in Nature Genetics has found a novel genetic link between the immune system and Parkinson’s Disease. The authors were screening for genomic variants unique to Parkinson’s patients, finding known ones but also a novel linkage. The link was with the HLA region, known to play a key role …

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Exciting stem cell progress on Alzheimer’s Disease

Test-for-Alzheimers-Disease

UPDATE: I have added more discussion at the bottom about therapeutics and how regenerative medicine might work for Alzheimer’s Disease. Alzheimer’s Disease (AD) is the most common cause of dementia throughout the world, affecting 10s of millions of people. The cost to society is staggering and on a personal level for those of us who …

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Huntington’s Disease, a major new finding

Huntingtons-Disease

This is the first post in a series focusing on stem cell advances related to specific diseases. Today we discuss Huntington’s Disease and a paper that came out yesterday in the journal Neuron that provides some significant insight into the mechanisms behind the disease. It is entitled: Huntingtin Is Required for Mitotic Spindle Orientation and …

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