What science and stem cell pubs are you reading right now and what do you hope to get too soon? Sometimes science means getting out in the field. Now there are no wild stem cells out there roaming the fields to catch and analyze, but there are other ways. A couple of my kids and […]
Weekly reads: Hox, exosome IND app, stem cell quiz, more Read More »
Graft-versus-host disease (GVHD) is counterintuitive In the weeks and months following a transplant, a major concern is the recipient’s immune system rejecting the “foreign” biological material. But in GVHD, the opposite happens: transplanted tissue unleashes a horde of T cells that spark a cascade of inflammation, within 100 days. Typically, GVHD follows a bone marrow
Mesoblast MSCs Quell Peds GvHD; On Road to FDA Approval? Read More »
Today’s post is the latest edition of my weekly recommended reads, which this week include Fate Therapeutics, COVID-19 updates, AAMC, and more including some great pubs such as one on 2 modes of PRC2 function. Also check out this handy resource: Helpful 2020 List of Stem Cell Journals and this blast from the past post of 10
Recommended reads: COVID-19 updates, FDA stem cell nod, PRC2, more Read More »
Stem cell clinics and suppliers have been getting into the business of making promotional films to generate more revenue, but now there’s something very different in the cinematic stem cell arena called From Jail Cell to Stem Cell by filmmaker Doug Orchard. It is at its heart an exposé film about some in my view particularly concerning stem
Review of clinic exposé film From Jail Cell to Stem Cell Read More »
What are you reading these days and does it include topics like cell therapies for COVID-19, ALS, regenerative potential of fibroblasts, and why Zoom meetings are so tiring for the brain? I cover those topics and more below with recommended reads including papers and media items. Here’s last week’s recommended reads. Here’s to fibroblasts, which
Weekend recommended reads: Athersys, ALS, COVID-19, Fibroblasts, Zoom brain Read More »
This is a post by Mina Kim, a UC Davis student intern for The Niche blog, about the main types of cellular therapies being studied clinically for COVID-19. During the novel coronavirus pandemic with millions of COVID-19 cases, the development of safe and effective treatments for patients is vital. Cellular medicine treatments are one of
Review of 4 cell therapy types under study for COVID-19 Read More »
What’s new this week in terms of reads includes a stem cell/drug combo for diabetic wonderments healing, more documentation of patient harms from stem cell clinics, and a list of recommending papers. Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice From a team of my UC Davis School of Medicine colleagues led
Weekly stem cell reads: diabetic wound healing, clinic bad outcomes, pubs list Read More »
The biotech Mesoblast is starting an expanded access study of its stem cell product for kids with a severe offshoot of COVID-19. The cellular drug in this case is remestemcel-L (more below). While most children fare better than adults in dealing with COVID-19, the rare subset of kids with COVID-19 for this study have more severe
New Mesoblast “COVID kid” stem cell study Read More »
My lab’s new paper in Communications Biology focused on high-grade pediatric glioma that have mutant histone variant H3.3 and we did something fairly novel that we are calling reciprocal CRISPR. Kids with these tumors have a near zero survival rate within a few years of diagnosis so we as a field desperately need something new to give
Reciprocal CRISPR gene editing in pediatric glioma: defining mechanisms & testing drugs Read More »
What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding
OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads Read More »