Search Results for: ES cell

Advice for new PIs part I: start before you start

August 2, 2010 / Professor Paul Knoepfler, Ph.D.

Update in 2020: It was kind of wild to read this post now so many years later as an “old” professor, seemingly ages from the realm of new PIs (principle investigators). What do you think? You can read more about the current state of our lab here. It’s an exciting feeling coming into a new […]

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Tumorigenicity and Pluripotency teased apart? Not yet for Myc

August 2, 2010 / Professor Paul Knoepfler, Ph.D.

Fig.-5-Nakagawa-et-al.-Myc-in-cancer-and-IPScs

A paper just came out in PNAS entitled “Promotion of direct reprogramming by transformation-deficient Myc“. The main thrust of this paper is that the tumorigenic and pluripotency-related functions of Myc could be separated. It focused primarily on the lesser studied LMyc. The topic of the intertwined good (pluripotency) and bad (tumorigenicity) functions of Myc, addressed

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