The mesenchymal stem cell (MSC). So important and yet so misunderstood? People pronounce it in different ways. People isolate the MSCs in different ways. Each person’s MSCs are very different. Each lab’s MSCs are different. (see picture above of MSCs showing fibroblastic morphology; source is Wikipedia) Someone once told me that MSCs are the same …
Would an MSC by any other name still smell as sweet? Read More »
One of the most exciting types of stem cells are mesenchymal stem cells or MSCs. Although there is some debate about these cells (e.g. I once heard Irv Weissman say at a meeting he wasn’t sure they really existed as such), a consensus would seem to be that they have great potential medical potential. Perhaps …
Mapping global trends in MSC & stem cell clinical trials: unexpected findings Read More »
I have a poll running regarding who would have been the best choice to share the Nobel Prize with Shinya Yamanaka and John Gurdon, and so far the winner is Ian Wilmut, who cloned the first mammal, Dolly the sheep. I should have included another option to indicate the possible preference that NO ONE should …
Wilmut voted most-deserving of 3rd Nobel slot with Yamanka & Gurdon in poll Read More »
I’m discussing the seamier side of science in a seven part series on what I call scientific sinning or the “seven sins of scientists”. The first four pieces in this series really stoked a great deal of interest and debate, covering Failure to Cite, Paper or grant killing, Need for Speed, and hype. Today in the fifth installment …
GO here for an even newer updated look at protecting one’s stem cells. Regenerative medicine is very exciting. But what’s even better than regenerative medicine? Preventative medicine. If one can prevent a problem from occurring in the first place, it is far better than trying to treat it after the fact. Of course in many …
Five simple ways to protect your stem cells to stay healthy and biologically younger Read More »
What does it take to succeed in science? Here are some key ingredients in my opinion after 22 years in academic science. Passion. One important ingredient that we cannot necessarily change significantly about ourselves, but that I think nonetheless is crucial for success, is a true excitement for science. Sometimes people even go so far …
While my gel was running….advice for success in science to newbies Read More »
I have in the past posted advice to new faculty and also top 10 advice list for the academic job hunt, but today I wanted to specifically talk about mentoring. Also, stay tuned for a special post later this week with an autobiographical section from Irv Weissman on his early career and who his key …
Irv Weissman’s lab came out with a very intriguing paper in Nature this week on regeneration and something called a blastema. Having a blastema It is not exactly on regenerative medicine of the kind we think about using exogenous stem cells, but more about how we might tap into nature’s own program for regeneration by …
If I only had a blastema: obstacles to human regeneration Read More »
At last year’s ISSCR 2010 Meeting in San Francisco, President Irv Weissman talked about the dangers of unvalidated stem cell treatments. He talked about the responsibility of stem cell scientists to stand against these and the importance for scientists not to endorse or serve on advisory committees of companies peddling such products and “therapies”. As …
Stem cell tourism: from bad to worse from 2010-2011 Read More »
Regenerative medicine is very exciting. But what’s even better than regenerative medicine? Preventative medicine. If one can prevent a problem for occurring in the first place, it is far better than trying to treat it after the fact. Of course in many cases we do not know the causes of diseases so it is difficult …