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Stem cell & regenerative medicine good news including Fate Therapeutics

January 13, 2019 / Professor Paul Knoepfler, Ph.D. / 6 Comments

In the past month or two there has been a steady stream of good news in the stem cell and regenerative medicine world. Here are three examples starting with Fate Therapeutics. Fate Therapeutics Fate Therapeutics announced the first US IND for an induced pluripotent stem cell (IPSC)-related product. Its cleared product, FT500, is an off-the-shelf […]

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Good final grades on my 20 x 2018 stem cell predictions

December 26, 2018 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Each year I make a list of stem cell predictions for the following year and I’ll release my predictions for 2019 soon, but first I’m grading how my 20 predictions for 2018 turned out. It seems I did better than usual predicting what would happen this year. I only got a couple partial credit or

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Mapping & driving the stem cell ecosystem: key points of my new paper

November 5, 2018 / Professor Paul Knoepfler, Ph.D. / 5 Comments

When you think of an ecosystem, do you imagine something like a forest or jungle full of different organisms? I usually do, but over the last few years I’ve also been thinking about this concept in a different way. I’ve been viewing the broad stem cell arena as an ecosystem. In that spirit, I’ve recently

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Magenta Therapeutics Good News-Bad News Trial Data

November 4, 2018 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Magenta Therapeutics is a biotech company with a portfolio including stem cell products. Their most well known investigational drug product is an expanded umbilical cord stem cell product called MGTA-456, an “ex-Novartis” product. Magenta just released new trial data on MGTA-456, which I see as a case of good news-bad news, and investors seem to

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A germinal list of 2019 stem cell meetings and conferences

September 28, 2018 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Here is my initial list of 2019 Stem Cell Meetings & Conferences. Send me your listings if you don’t see your meeting here so I can start fleshing out the list more. Meeting listings are not endorsements and I try to make this list fairly comprehensive of as many stem cell meetings as I can.

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2019 Stem Cell Meetings List

September 24, 2018 / Professor Paul Knoepfler, Ph.D.

Here is our listing of 2019 Stem Cell Meetings & Conferences. Send me your listings if you don’t see your meeting here. Meeting listings are not endorsements and I try to make this list fairly comprehensive. January ARM Cell & Gene Therapies State of the Industry Briefing San Francisco, CA, USA (Held January 7, 2019)

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CRISPR update: lots of new pubs, news, & maybe a patent finale

September 13, 2018 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Figure-1a-from-Akcakaya-et-al.-paper-Nature-2018

Sometimes it seems like a bunch of stuff in one area, like with CRISPR this week, happens all of a sudden in science. A bunch of fairly high-profile gene editing pubs came out. They generated a lot of news reports. Other news in this arena popped up too, all within a few days. In vivo

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Some stem cell good news, stuff for debate, & cool pubs

September 9, 2018 / Professor Paul Knoepfler, Ph.D. / 2 Comments

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Sometimes we could all use a jolt of good news and cool science. Those of us in the stem cell field probably get tired at times of all the bad-ish, even if important news (like this from Michael Hiltzik of the LA Times) out there surrounding certain unproven stem cell offerings and also clinics that

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Attorney Jaffe, fan of less oversight, still clobbers Florida stem cell clinic firm

August 5, 2018 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Attorney Richard Jaffe, who has been an advocate for clinics to have the right to sell and patient to buy unproven therapies such as the stem cells sold by clinics and unproven cancer therapies, just did a kind of shocking u-turn on a specific point. Jaffe and I have very different philosophical views of the

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Mixed Nuffield Council Report Too Aspirational on Human Genetic Modification

July 19, 2018 / Professor Paul Knoepfler, Ph.D. / 2 Comments

It’s an odd confluence of events this week that (A) the Nuffield Council, an ethics think tank, gives a thumbs up in a new report to heritable human genetic modification that would probably include using CRISPR in the same week that (B) a new paper reports that CRISPR can cause unpredictable genomic damage and several other concerning reports

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