In a major first for the stem cell and regenerative medicine fields, a patient in Japan today received a pioneering transplant of a retinal pigmented epithelial (RPE) sheet made from induced pluripotent stem (iPS) cells, also known by the acronym IPSC. This is the first ever iPS cell-based transplant into a human. The patient is …
Landmark: patient receives first ever iPS cell based transplant Read More »
A paper has been published reporting that repeated attempts to make so-called “acid bath stem cells” have failed. At the end of January it was claimed in two Nature papers that a mild acid treatment created pluripotent or even totipotent stem cells that that the authors termed “STAP cells” or “STAP stem cells” (collectively referred …
Perspectives on Lee Lab F1000 Paper that STAP Cell Method Does Not Work Read More »
The future is now. Or so goes the expression. For CIRM, it rings true today. Last year I blogged about what we might expect from the new CIRM that would evolve and take form in the future. I was particularly thinking about this coming incarnation of CIRM, which I called CIRM 2.0, as it related …
A new human therapeutic cloning paper is out today, the third in a matter of months. This one is from the lab group of Dr. Dieter Egli published in Nature demonstrating production of nuclear transfer embryonic stem cells (NT-ESCs) from an adult human somatic donor via somatic cell nuclear transfer (SCNT). This human SCNT paper follows …
Cloning is cloned again: New Nature Paper is 3rd on Human SCNT Read More »
Advanced Cell Technology (ACT; $ACTC) has a new paper out on using human embryonic stem cells (hESC) to make MSCs with potentially powerful therapeutic potential. The paper, entitled Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties, was published in the journal Stem Cells and Development. What’s the scoop on this …
A team at the Weizmann Institute of Science in Israel led by Jacob Hanna reports today near perfect reprogramming efficiency to make induced pluripotent stem cells (iPSCs) by eliminating a single factor called Mbd3 from the cellular equation. On first glance, the Nature article (Rais, et al.) seems to be all about boosting cellular reprogramming efficiency to close …
100% reprogramming efficiency reports Jacob Hanna Read More »
One of the more controversial areas in the stem cell field has been over a stem cell type that only a handful of researchers have been able to find and study: very small embryonic-like stem cells or VSELs. These days some are calling them V-cells too. I’ve been getting an increasing number of questions from …
What are VSELs and why are more clinics selling them? Read More »
By Dr. Susan Lim A record 4100 delegates attended the 11th Annual Meeting of the International Society for Stem Cell Research (ISSCR), held at the Convention and Exhibition Center in Boston from 12-15 June 2013. Co-sponsored by the Harvard Stem Cell Institute, the Meeting featured 7 Plenary sessions including a Presidential Symposium, 20 concurrent scientific …
Delightful overview of ISSCR 2013 by guest blogger Dr. Susan Lim Read More »
By Jeanne Loring. On Wednesday afternoon at the ISSCR meeting in Boston, Jamie Thomson gave a talk about the history of human pluripotent stem cells. There were probably only a dozen people in the audience of around 3,000 who were working on human ES cells around the same time that Jamie and Joseph Itskovitz-Eldor were …
Jeanne Loring’s Thought-Provoking Guest Post on Jamie Thomson’s ISSCR Talk Read More »
Τι είναι τα βλαστοκύτταρα; Greek. Τι είναι τα βλαστοκύτταρα; Το ανθρώπινο σώμα περιέχει εκατοντάδες διαφορετικά είδη κυττάρων που είναι απαραίτητα για την καθημερινή μας υγεία. Τα κύτταρα αυτά είναι υπεύθυνα για διάφορες βασικές λειτουργίες, όπως το να κάνουν την καρδιά μας να χτυπά, τον εγκέφαλό μας να σκέφτεται, τα νεφρά μας να καθαρίζουν το αίμα, …