I have a soft spot for fibroblasts, perhaps because one of the first immortalized cell lines I ever grew was NIH3T3. These are mouse fibroblasts that have been immortalized. They are very useful for a variety of experiments. I used them to study an oncogene called E2A-PBX1. Experience with fibroblasts including 3T3s I was amazed …
Weekly reads: fibroblasts, gene-editing, Mitalipov, personhood, embryos Read More »
What are you reading these days and does it include topics like cell therapies for COVID-19, ALS, regenerative potential of fibroblasts, and why Zoom meetings are so tiring for the brain? I cover those topics and more below with recommended reads including papers and media items. Here’s last week’s recommended reads. Here’s to fibroblasts, which …
Weekend recommended reads: Athersys, ALS, COVID-19, Fibroblasts, Zoom brain Read More »
The Niche has had many authors over the years, focusing on expertise in the biomedical arena and in particular related to stem cells. I’ve invited many authorities in particular areas to write posts. Over the years I’ve written probably 99+% of the posts here on The Niche, but we’ve also had some great guest authors …
Working together with ISSCR, last week I held a short essay contest for a free registration to ISSCR 2014 in Vancouver. I received some great entries so it was a challenge to pick just one, but the winning piece was written by student Mohamed Gatie. Congratulations to Mohamed. I hope to meet him in the Vancouver …
By Dr. Susan Lim A record 4100 delegates attended the 11th Annual Meeting of the International Society for Stem Cell Research (ISSCR), held at the Convention and Exhibition Center in Boston from 12-15 June 2013. Co-sponsored by the Harvard Stem Cell Institute, the Meeting featured 7 Plenary sessions including a Presidential Symposium, 20 concurrent scientific …
Delightful overview of ISSCR 2013 by guest blogger Dr. Susan Lim Read More »
Cancer Stem Cells: a new target Disease Focus Series: Cancer Disease Focus Series: HIV/AIDS Disease Focus Series: Spinal Cord InjuryDisease Focus Series: Osteoarthritis research moving forward Disease Focus Series: Parkinson’s Disease and promising new pre-clinical results from iPS cells Disease Focus Series: a big week of exciting progress on Alzheimer’s Disease Alzheimer’s Disease Disease Focus …
I recently did a post telling you about one of my favorite molecules, Myc, which is important not only in cancer but also in most, if not all stem cells including iPS cells. There’s a lot more to Myc and how it does it’s tricks in embryonic stem cells and iPS cells. It cannot do …
It has been a week to think about mentors and I posted somewhat autobiographically on how to find and be a good mentor a few days ago. Also along these lines, I asked one of the great mentors of all time, Irv Weissman, about his early career and who were the mentors that made the …
The tragic 9.0 earthquake and tsunamis that hit Japan a few weeks ago are having lasting consequences not only for Japan, but also for the world via radiation. One area of particular concern is the radiation that has leaked and is continuing to leak from the damaged nuclear reactors. At this point, the radiation …
A reality check on the radiation spreading across the globe Read More »
People often ask me about stem cells for autism or even their hope of an autism cure. I’ve explained that there is no new treatment for autism based on stem cells. There aren’t even mildly encouraging data. Note that it can be hurtful to the community to talk about an autism cure and disregarding neurodiversity. …