Why aren’t there are super pygmy vertebrates? For most vertebrate animals, their early embryonic development unfolds in extremely congruent fashions. Embryo growth is stem cell-dependent and in large part, despite different gestational periods, the molecular and cellular machinery that controls vertebrate development is almost perfectly conserved. Yet at maturity vertebrates end up with a range […]
Why aren’t there vertebrate super pygmies? Read More »
Why do people have such a big brain compared to other animals? Vertebrate embryonic development is a highly conserved process, particularly in the earliest phases. (note: you may find this September 2020 post on regulation of bee brain size to be interesting.) A wide variety of vertebrate animals including humans start out with embryonic body plans
Why is the human brain super-sized? Read More »
Sometimes a top scientist makes news with a quote on research and that happened with Ian Wilmut recently on stem cells. Move away from research on human ES cells (hESC) in favor of very new and still largely unclear trans-differentiation technology? I say, no way. But, Bradley Fikes of the North County Times has reported
Ian Wilmut, Dolly’s dad, says dump hESC? What does this mean? Read More »
Many of us have been discouraged by Geron’s decision to end their stem cell program, which included products based on human embryonic stem (ES) cells, but let’s keep some perspective on this and not give up hope. The opponents of hope want us to give up. They who have waged their own self-proclaimed war on
Keep hope: the ‘war’ is not over Read More »
As much as so many were excited yesterday about the enrollment of the first patient in a CIRM-funded clinical trial, I did not see a mention of a very important element. The patient. Our excitement about the clinical trial moving forward is understandable, but we also need to keep a sober perspective on the fact
The news of CIRM and clinical trial: don’t forget the patient Read More »
When does politics trump hope? It seems all the time. I think politicians frequently take positions on science-related issues that they either don’t really believe or understand. Perhaps I’m wrong, but for example, I don’t believe that most national level Republican leaders oppose ES cell research. Most of us have either ourselves faced injuries or
The FDA has given Advanced Cell Technology (ACT) the go ahead to begin their clinical trial using retinal progenitor cells derived from hESC by clearing the company’s IND application, bringing hope to those with vision loss and even blindness. The trial will be a combined Phase I/II to treat Stargardt’s Macular Dystrophy and has huge