Search Results for: mitochondrial disease

Grading my stem cell predictions for 2016: how’d I do?

stem-cell-predictions

Below are the 2016 stem cell predictions I made last year and their status now color-coded near year’s end. Green is right, orange is mixed bag, and red is flat out wrong. Overall, I did better than most past years with only having entirely blown it on four. Stay tuned later this week for my 2017 predictions, …

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20 Nominees for Stem Cell Person of the Year 2016 Award

Stem-cell-person-of-the-year-award

I received a score of great nominations for the Stem Cell Person of the Year 2016 Award and have briefly described the twenty nominees below. The point of the award is to honor the top positive stem cell leader who specifically thinks outside the box and takes risks. I’ve started an on-line vote where you can vote once per day for …

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Yamanaka’s baby turns 10: ten IPS cell hot button bullet points

Nobel Laureate Shinya Yamanaka, the first to produce induced pluripotent stem cells

Has it really been 10 years since induced pluripotent stem cells (aka IPS cells or IPSC) came onto the scene in the stem cell field? Yes, it was a decade ago that now Nobel Laureate Shinya Yamanaka (山中伸弥) published that seminal Cell paper on reprogramming to make mouse IPS cells and then human IPS cells …

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Stem cell checkup: how are my 2016 predictions doing half way?

Stem-Cell-Predictions

Each December I make stem cell predictions for the coming year and I did that for 2016 where I made 20 predictions. At around mid year I do a checkup on how my predictions are doing halfway and that is the purpose of this post. Below are my predictions that I made in 2015 for stem …

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New chat with George Church on CRISPR’ing people, Zika, weapons, & more

George-Church

I talked last year about human genetic modification by CRISPR with George Church a year ago. Now we’ve followed up with a long chat on this topic going into much more detail and with questions on recent developments. Each question is listed numerically and then there is a back and forth on that question with George …

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New Mitalipov paper on stem cell mitochondria: challenge for IPS cell field?

Mitalipov-mitochondrial-mutations

A new paper from Shoukhrat Mitalipov’s lab on stem cell mitochondria points to a pattern whereby induced pluripotent stem (IPS) cells tend to have more problems if they are from older patients. What does this paper mean for the stem cell field and could it impact more specifically the clinical applications of IPS cells? The new …

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Kelly Hills interview: human genetic modification & bioethics

Kelly-Hills

Below is a conversation with bioethics commentator Kelly Hills (who BTW has a great blog), tackling some of the key issues surrounding the potential use of CRISPR-Cas9 technology to make heritable human genetic modification. I really appreciate her clear and insightful answers to some tough questions that many are grappling with today on this topic. Part …

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Nita Farahany Interview on Human Germline Modification: Defining A Road Forward

Nita-Farahany

The topic of heritable human genetic modification has been heating up recently. Prominent scientists, ethicists, and legal scholars have being weighing in, and there is a range of attitudes. Some favor a complete, moratorium including even lab work, while on the other end of the spectrum there are those who have a more liberal perspective. Many …

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