September 19, 2020

The Niche

Knoepfler lab stem cell blog

3 min read

As the year comes to a close this week, it is a good time to look back on 2010 and consider the major events in the stem cell field and give out awards. Stem Cell Event of the Year. I would give this award as a dual prize to Geron and Advanced Cell Technology (ACT) for them receiving FDA approval to begin their hESC-based clinical trials for spinal cord injury and blindness respectively. Both Geron and ACT have made history. Hopefully they will receive …Read More

2 min read

My lab studies iPS cells. We are excited about iPS cells and they have enormous potential. However, there are some realities about iPS cells related to safety that impede our ability to use them to treat patients any time soon. We must solve these roadblocks before we can move forward, but interestingly, these facts are only rarely discussed. 1) During iPS cell formation, many non-iPS cell colonies are created side-by-side in the same dish and many of them are composed of cancer cells. As …Read More

2 min read

The DC Appeals Court hears oral arguments today in the case over whether the federal government can legally fund embryonic stem cell (ESC) research. At stake are dozens of research projects that could provide treatments or cures for millions of Americans. Reportedly, an amicus brief to the court has been filed on behalf of Associate Professor Maureen L. Condic of the University of Utah. Dr. Condic argues, much the same as plaintiff in the case James Sherley, that the issue of when life begins …Read More