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Stem cell good news briefs: TiGenix, Asterias, CIRM, Awards, & More

September 1, 2015 / Professor Paul Knoepfler, Ph.D. / 4 Comments

There’s a growing stream of stem cell good news of late. Stem cell biotech, TiGenix, reported encouraging Phase 3 allogeneic results on stem cells. A big milestone. I can’t wait to see the actual data. Its product, Cx601, has so far been safe and effective for perianal fistulas in Crohn’s disease. See more from Alexey on this. CIRM has funded the largest […]

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Michael Cea ISSCR chat with Jeanne Loring on stem cell field

August 5, 2015 / Professor Paul Knoepfler, Ph.D. / 3 Comments

ISSCR Chat By Michael Cea Jeanne Loring of the Scripps Research Institute in La Jolla, California kindly sat down with me at the ISSCR annual meeting for a broad discussion of her history, views on the field and developments in the science. I found Jeanne a refreshing character, as I did a number of others I was

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Historic turning point for IPS cell field in Japan?

August 2, 2015 / Professor Paul Knoepfler, Ph.D. / 24 Comments

As many of you know, the pioneering, first of its kind IPS cell clinical study in Japan has been suspended as I first blogged about here.2020 Update: I believe a version of this study is ongoing. In the comments section of that blog post there has been a helpful overall discussion that has involved Dr.

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Masayo Takahashi (高橋政代) on IPSC Trial for Vision

July 7, 2015 / Professor Paul Knoepfler, Ph.D. / 9 Comments

Masayo Takahashi (高橋政代) on IPSC Trial for Macular Degeneration By Michael Cea Stem Cell Analyst & Advocate (editor’s note: piece was originally posted on Michael’s blog here; follow Michael on Twitter @msemporda) Masayo Takahashi interview Having followed closely the developments in programs using pluripotent based therapeutics I was fortunate during ISSCR2015 to have the opportunity to

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Biotech Talks #ISSCR2015: StemCells Inc, Semma, ViaCyte, & Le Blanc

June 27, 2015 / Heather Main / 1 Comment

The path to the clinic is a slow and arduous activity, frustrating not only to the researcher and patient, but investors and biotech companies. Successful clinical translation of technologies requires a balance of science, streamlined translation and funding. To develop fantastic science and then realise the most important components cannot be adapted to the clinical

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Was Fujifilm CDI acquisition a good move by the companies?

March 31, 2015 / Professor Paul Knoepfler, Ph.D. / 4 Comments

The big stem cell news already this week is the acquisition by Fujifilm of Cellular Dynamics International (CDI) for a whopping $307 million dollars or about $16.50 per CDI share. You can read the press release here. Update: The entity is now known as Fujifilm Cellular Dynamics. It was less than two years ago that CDI did

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Are babies from same-sex couples possible?

March 3, 2015 / Professor Paul Knoepfler, Ph.D. / 9 Comments

A question that has come up with advances in stem cell technology: could same-sex couples have their own biological children? Since Shinya Yamanaka reprogrammed first mouse and then human ordinary cells into powerful pluripotent stem cells, termed induced pluripotent stem (iPS) cells, back in 2006-2007 many new research avenues have opened up. The impossible suddenly

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Can hearts fix themselves via stem cells?

January 6, 2015 / Professor Paul Knoepfler, Ph.D. / 5 Comments

Can hearts repair themselves via stem cell mechanisms including possibly their own stem cells? It’s a hot topic question at the center of a big debate in the stem cell field. My inclination at present is that the answer is most likely “no” at this point, but that could change and it’s important to keep

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Post-Publication Paper Reviews & Commentaries

January 2, 2015 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

2015 Review of Vogelstein “Bad Luck” Cancer & Stem Cell Paper in Science January 02, 2015 2014 What Does New Paper Mean for Future of Nuclear Transfer ES Cells? November 9, 2014 Encouraging New Paper on ACT Stem Cell-Based Trial for Macular Degeneration October 14, 2014 Top 10 Takeaways From Harvard Stem Cell Diabetes

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Grad student Gonçalo Rodrigues Wins Free Registration to WAFSF Stem Cell Meeting

November 5, 2014 / Professor Paul Knoepfler, Ph.D.

I put out a call for a flash contest for people to win free registrations to the great stem cell meeting, WAFSF, starting tomorrow in SFO (see meeting info here). The winner is Gonçalo Rodrigues (pictured at right) of UC Berkeley, a visiting Ph.D. student from Portugal. Here’s what he told me as the reason why

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